Browsing University of Waterloo by Type "Article"
Now showing items 21-40 of 1931
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The action mechanism of daptomycin
(Elsevier, 2016-12-15)Daptomycin is a lipopeptide antibiotic produced by the soil bacterium Streptomyces roseosporus that is clinically used to treat severe infections with Gram-positive bacteria. In this review, we discuss the mode of action ... -
Active Navigation in Virtual Environments Benefits Spatial Memory in Older Adults
(MDPI, 2019-03)We investigated age differences in memory for spatial routes that were either actively or passively encoded. A series of virtual environments were created and presented to 20 younger (Mean age = 19.71) and 20 older (Mean ... -
Acute effects of aerobic exercise on cognitive function in individuals with Parkinson’s disease
(Elsevier, 2018-04-03)Deficits in executive functions are highly prevalent in Parkinson’s disease (PD). Although chronic physical exercise has been shown to improve executive functions in PD, evidence of acute exercise effects is limited. This ... -
An Acyl-Linked Dimer of Daptomycin Is Strongly Inhibited by the Bacterial Cell Wall
(American Chemical Society, 2017-03-28)The lipopeptide antibiotic daptomycin is active against Gram-positive pathogens. It permeabilizes bacterial cell membranes, which involves the formation of membrane-associated oligomers. We here studied a dimer of daptomycin ... -
An adaptive variational finite difference framework for efficient symmetric octree viscosity
(ACM, 2019-07)While pressure forces are often the bottleneck in (near-)inviscid fluid simulations, viscosity can impose orders of magnitude greater computational costs at lower Reynolds numbers. We propose an implicit octree finite ... -
Additively manufactured metallic biomaterials
(Elsevier, 2021-12)Metal additive manufacturing (AM) has led to an evolution in the design and fabrication of hard tissue substitutes, enabling personalized implants to address each patient's specific needs. In addition, internal pore ... -
Addressing Health Care Needs For Frail Seniors In Canada: The Role of InterRAI Instruments
(Canadian Geriatrics Society, 2013-12-30)Fiscal pressure on the Canadian health care system results from rising numbers of frail seniors with multiple concurrent medical co-morbidities and geriatric syndromes. Improving outcomes in such seniors is contingent on ... -
Addressing Systemic Barriers to Truth and Reconciliation in Canadian Higher Education Institutions
(University of Waterloo, 2022-06-24)Education served as a driving force for the colonization of Indigenous Peoples in what is now known as Canada. Today, education is essential for truth and reconciliation. In 2015, the Truth and Reconciliation Commission ... -
Adsorption and Desorption of DNA on Graphene Oxide Studied by Fluorescently Labeled Oligonucleotides
(American Chemical Society, 2011-03-15)Being the newest member of the carbon materials family, graphene possesses many unique physical properties resulting is a wide range of applications. Recently, it was discovered that graphene oxide can effectively adsorb ... -
Adsorption of DNA Oligonucleotides by Titanium Dioxide Nanoparticles
(American Chemical Society, 2014-01-28)Titanium dioxide (TiO2) or titania shows great promise in detoxification and drug delivery. To reach its full potential, it is important to interface TiO2 with biomolecules to harness their molecular recognition function. ... -
Adsorption of DNA onto gold nanoparticles and graphene oxide: surface science and applications
(Royal Society of Chemistry, 2012-06-28)The interaction between DNA and inorganic surfaces has attracted intense research interest, as a detailed understanding of adsorption and desorption is required for DNA microarray optimization, biosensor development, and ... -
Adsorption of Nanoceria by Phosphocholine Liposomes
(American Chemical Society, 2016-12-13)Nanoceria (CeO2 nanoparticle) possesses a number of enzyme-like activities. In particular, it scavenges reactive oxygen species based on in-vitro and in vivo antioxidation studies. An important aspect of fundamental physical ... -
Adsorption of surface-modified silica nanoparticles to the interface of melt poly (lactic acid) and supercritical carbon dioxide
(ACS Publications, 2015-04-28)With the purpose of fabricating polymer nanocomposite foams and preventing coalescence in foaming processes, the interfacial tension of poly (lactic acid) (PLA) -silica composites is investigated in this work. Synthesized ... -
Advanced material applications of starch and its derivatives
(Elsevier, 2018-11-01)Starch as a natural polymer has attracted significant interest and is currently used in numerous industrial applications. This is because of its renewability, biodegradability, abundance, and cohesive film-forming properties. ... -
Advancing the evidence to improve the nutrition of populations: a refreshed vision and scope for Nutrition Journal
(Springer, 2017-07)This editorial introduces a revised and refreshed scope for Nutrition Journal, one of BioMed Central’s open access journals. Diet is among the leading risk factors for morbidity and mortality globally [1]. This signals the ... -
Adverse events among Ontario home care clients associated with emergency room visit or hospitalization: a retrospective cohort study
(BioMed Central, 2013-06-22)Background: Home care (HC) is a critical component of the ongoing restructuring of healthcare in Canada. It impacts three dimensions of healthcare delivery: primary healthcare, chronic disease management, and aging at home ... -
Adverse Events Associated with Hospitalization or Detected through the RAI-HC Assessment among Canadian Home Care Clients
(Longwoods Publishing, 2013-08-19)Background: The occurrence of adverse events (AEs) in care settings is a patient safety concern that has significant consequences across healthcare systems. Patient safety problems have been well documented in acute care ... -
Age-Related Changes in Vibro-Tactile EEG Response and Its Implications in BCI Applications: A Comparison Between Older and Younger Populations
(IEEE, 2019-04)The rapid increase in the number of older adults around the world is accelerating research in applications to support age-related conditions, such as brain-computer interface (BCI) applications for post-stroke neurorehabilitation. ... -
Agency and Amplification: A Comparison of Manual and Computational Thematic Analyses by Public Health Researchers
(ACM, 2023-01)Computational techniques offer a means to overcome the amplified complexity and resource-intensity of qualitative research on online communities. However, we lack an understanding of how these techniques are integrated by ... -
Agent-Based Modeling Approach to Investigating the Impact of Water Demand Management
(American Society of Civil Engineers, 2018-03-01)This paper proposes an agent-based modeling approach to assess water users' behavior for water demand management (WDM) in a river basin. In this procedure, each agent controls its own strategy regarding whether to conserve ...