Browsing University of Waterloo by Subject "hippocampus"
Now showing items 1-8 of 8
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Are There Sex-Linked Differences Across the Longitudinal Axis of the Rat Hippocampus Following Ischemic Injury?
(University of Waterloo, 2016-10-14)Ischemic strokes occur when an occluded blood vessel limits the delivery of oxygen and nutrients to neurons, and can result in widespread cell death. Although stroke is the third leading cause of death and a major cause ... -
Does maternal obesity affect hippocampal-dependent spatial learning and memory retention in offspring?
(University of Waterloo, 2015-10-02)With a rise in the prevalence of obesity worldwide, behavioural, as well as physiological changes after consumption of a high-fat diet are becoming increasingly recognized. In addition to increased risk of chronic and ... -
Effects of acute exercise and voluntary freewheel exercise in mice on pro-inflammatory cytokines and markers of apoptosis in the hippocampus
(University of Waterloo, 2011-09-01)Introduction: Alzheimer’s disease (AD) and dementias constitute a significant public health burden and it is estimated that one in 85 people may be living with AD by 2050. Dementias are a spectrum of diseases with common ... -
Exploring the Ventral Hippocampal Formation
(University of Waterloo, 2014-10-23)The hippocampus (HC) is important for both memory and spatial navigation. These functions are thought to be supported by spatial firing patterns of "place cells" which are active in only certain locations within environments. ... -
Investigating the Effects of Methylmercury on Tetanus Induced Synaptic Plasticity in CA1 of Rat Hippocampus Using A Newly Developed MEA Protocol
(University of Waterloo, 2019-10-22)Background: Methylmercury (MeHg) is a neurotoxicant that induces sensorimotor dysfunction at high levels. However, the majority of the world’s populations are exposed at lower levels, at which the effects and mechanisms ... -
A Mathematical Model of CA1 Hippocampal Neurons with Astrocytic Input
(University of Waterloo, 2009-06-22)Over time astrocytes have been thought to function in an auxiliary manner, providing neurons with metabolic and structural support. However, recent research suggests they may play a fundamental role in the generation and ... -
Mean-field models for heterogeneous networks of two-dimensional integrate and fire neurons
(Frontiers Media, 2017-12-27)We analytically derive mean-field models for all-to-all coupled networks of heterogeneous, adapting, two-dimensional integrate and fire neurons. The class of models we consider includes the Izhikevich, adaptive exponential ... -
Motivational State Influences the Content of Hippocampal Sequences
(University of Waterloo, 2015-08-18)Hippocampal sharp wave-ripple (SWR) associated sequence activity, commonly referred to as replay, has generally been thought of as mediating the transfer of recent experience into the neocortex. However, a number of ...