Browsing Waterloo Institute for Nanotechnology by Title
Now showing items 107-126 of 193
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In Vitro Selection of a New Lanthanide-Dependent DNAzyme for Ratiometric Sensing Lanthanides
(American Chemical Society, 2014-10-07)Developing biosensors for lanthanides is an important but challenging analytical task. To address this problem, in vitro selection of RNA-cleaving DNAzymes was carried out using a library containing a region of 35 random ... -
In Vitro Selection of Chromium-Dependent DNAzymes for Sensing Chromium(III) and Chromium(VI)
(Wiley, 2016-07-04)Chromium is a very important analyte for environmental monitoring, and developing biosensors for chromium is a long-standing analytical challenge. In this work, in vitro selection of RNA-cleaving DNAzymes was carried out ... -
In-situ observation of nucleation and property evolution in films grown with an atmospheric pressure spatial atomic layer deposition system.
(IOP Science, 2020-06-01)Atmospheric pressure—spatial atomic layer deposition (AP-SALD) is a promising open-air deposition technique for high-throughput manufacturing of nanoscale films, yet the nucleation and property evolution in these films has ... -
Instantaneous and Quantitative Functionalization of Gold Nanoparticles with Thiolated DNA Using a pH-Assisted and Surfactant-Free Route
(American Chemical Society, 2012-05-02)The attachment of thiolated DNA to gold nanoparticles (AuNPs) has enabled many landmark works in nanobiotechnology. This conjugate chemistry is typically performed using a salt-aging protocol where, in the presence of an ... -
Instantaneous Attachment of an Ultrahigh Density of Nonthiolated DNA to Gold Nanoparticles and Its Applications
(American Chemical Society, 2012-12-11)The last 16 years have witnessed the landmark development of polyvalent thiolated DNA-functionalized gold nanoparticles (AuNP's) possessing striking properties within the emerging field of nanobiotechnology. Many novel ... -
Interfacing Zwitterionic Liposomes with Inorganic Nanomaterials: Surface Forces, Membrane Integrity, and Applications
(American Chemical Society, 2016-05-10)Zwitterionic phosphocholine (PC) lipids are the main constituent of the mammalian cell membrane. PC bilayers are known for their antifouling properties, yet they are adsorbed by all tested inorganic nanoparticles. This ... -
Intracellular Detection of ATP Using an Aptamer Beacon Covalently Linked to Graphene Oxide Resisting Nonspecific Probe Displacement
(American Chemical Society, 2014-12-16)Fluorescent aptamer probes physisorbed on graphene oxide (GO) have recently emerged as a useful sensing platform. A signal is generated by analyte-induced probe desorption. To address nonspecific probe displacement and the ... -
Iron oxide nanozyme catalyzed synthesis of fluorescent polydopamine for light-up Zn2+ detection
(Royal Society of Chemistry, 2016-07-29)Fluorescent polydopamine (FPD) is an interesting material with excellent biocompatibility. However, its preparation is currently a lengthy and potentially dangerous process. We herein employ magnetic iron oxide (Fe3O4) ... -
Label-Free Ag+ Detection by Enhancing DNA Sensitized Tb3+ Luminescence
(Multidisciplinary Digital Publishing Institute, 2016-08-26)In this work, the effect of Ag+ on DNA sensitized Tb3+ luminescence was studied initially using the Ag+-specific RNA-cleaving DNAzyme, Ag10c. While we expected to observe luminescence quenching by Ag+, a significant ... -
Light-Activated Metal-Coordinated Supramolecular Complexes with Charge-Directed Self-Assembly
(American Chemical Society, 2013-02-21)Metal-coordinated materials are attractive for many applications including catalysis, sensing, and controlled release. Adenine and its derivatives have been widely used to generate many coordination complexes, polymers, ... -
Liposome Supported Metal Oxide Nanoparticles: Interaction Mechanism, Light Controlled Content Release and Intracellular Delivery
(Wiley, 2014-05-26)Zwitterionic phosphotydylcholine liposomes stably adsorb a number of metal oxide nanoparticles via its phosphate group. This is different from physisorption and fusion with SiO2. The hybrid materials can be internalized ... -
Liposome/Graphene Oxide Interaction Studied by Isothermal Titration Calorimetry
(American Chemical Society, 2015-03-15)The interaction between graphene oxide (GO) and lipid bilayers is important for fundamental surface science and many applications. In this work, isothermal titration calorimetry (ITC), cryo-TEM, and fluorescence spectroscopy ... -
Magnetic Iron Oxide Nanoparticle Seeded Growth of Nucleotide Coordinated Polymers
(American Chemical Society, 2016-06-22)The introduction of functional molecules to the surface of magnetic iron oxide nanoparticles (NPs) is of critical importance. Most previously reported methods were focused on surface ligand attachment either by physisorption ... -
Magnetic nano-nets for capture of microbes in solution based on physical contact
(Elsevier, 2019-02-01)Self-assembly of Au nanoparticles with Fe ions is used to develop magnetic nano-nets similar to fishing nets for capture and removal of microbes in aqueous medium. The nano-nets have a high aspect ratio, span microns in ... -
Mechanisms of DNA Sensing on Graphene Oxide
(American Chemical Society, 2013-08-20)Adsorption of a fluorophore-labeled DNA probe by graphene oxide (GO) produces a sensor that gives fluorescence enhancement in the presence of its complementary DNA (cDNA). While many important analytical applications have ... -
Metal-Induced Specific and Nonspecific Oligonucleotide Folding Studied by FRET and Related Biophysical and Bioanalytical Implications
(Wiley, 2012-01-13)Metal induced nucleic acid folding has been extensively studied with ribozymes, DNAzymes, tRNA and riboswitches. These RNA/DNA molecules usually have a high content of double-stranded regions to support a rigid scaffold. ... -
Microparticle suspensions and bacteria laden droplets: Are they the same in terms of wetting signature?
(ACS, 2021-01-17)Adhesion behavior of microbial pathogens on commonly encountered surfaces is one of the most pertinent questions now. We present the characterization of bacteria laden droplets and quantify the adhesion forces on highly ... -
Molecular Beacon Lighting up on Graphene Oxide
(American Chemical Society, 2012-05-01)A molecular beacon (MB) is comprised of a fluorophore and a quencher linked by a DNA hairpin. MBs have been widely used for homogeneous DNA detection. In addition to molecular quenchers, many nanomaterials such as graphene ... -
Molecularly Imprinted Polymers with DNA Aptamer Fragments as Macromonomers
(American Chemical Society, 2016-03-16)Molecularly imprinted polymers (MIPs) are produced in the presence of a template molecule. After removing the template, the cavity can selectively rebind the template. MIPs are attractive functional materials with a low ... -
Multicopper Laccase Mimicking Nanozymes with Nucleotides as Ligands
(American Chemical Society, 2017-01-18)Using nanomaterials to achieve functional enzyme mimics (nanozymes) is attractive for both applied and fundamental research. Laccases are multicopper oxidases highly important for biotechnology and environmental remediation. ...