Browsing Theses by Author "Trainor, Kyle"
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Adnectin Solubility and Dynamics
Trainor, Kyle (University of Waterloo, 2019-10-28)Rapid growth of the global market for monoclonal antibodies (mAbs) has generated considerable interest in the development of alternative molecules that facilitate rapid discovery and manufacturing, while replicating the ... -
Inclusion Body Formation by Mutants of the Tenth Human Fibronectin Type III Domain
Trainor, Kyle (University of Waterloo, 2015-04-16)Inclusion bodies (IBs) are intracellular, insoluble protein aggregates, commonly observed when a protein of interest is expressed at high concentrations in a bacterial cell-based expression system. The molecular determinants ...