Browsing Theses by Author "Bradley, Ryan M."
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Functional characterization of murine 1-acylglycerol-3-phosphate O-acyltransferase 4 (AGPAT4)
Bradley, Ryan M. (University of Waterloo, 2015-09-30)The human genome project has allowed for the rapid identification of a large number of protein families based on similarities in their genetic sequences. The acyl-glycerol phosphate acyltransferase (AGPAT) family of enzymes ... -
Identification and characterization of a novel microsomal enzyme involved in cardiolipin synthesis and remodeling
Bradley, Ryan M. (University of Waterloo, 2018-05-17)Cardiolipin (CL) is a specialized dimeric phospholipid predominantly found in the inner mitochondrial membrane in eukaryotes. Following de novo synthesis, the acyl chains of CL are remodeled in a manner that is tissue- and ...