Browsing Theses by Author "Ma, Lingzi"
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In Vitro Selection, Characterization, and Application of a Sodium-Dependent DNAzyme and a Metal-Independent Ribozyme
Ma, Lingzi (University of Waterloo, 2021-09-20)Ribozymes and DNAzymes are collectively called catalytic nucleic acids. Compared to protein enzymes, catalytic nucleic acids are programmable in structure, easy to synthesize or modify, and more chemically stable especially ... -
A New Na(+)-specific DNAzyme Mutant from in Vitro Selection
Ma, Lingzi (University of Waterloo, 2017-09-08)Sodium is one of the most ubiquitous metal ions in both intracellular and extracellular fluids. Many fluorescent sensors have been designed to measure Na+ concentrations. However, Na+ binding to biomolecules such as DNA ...