Browsing Theses by Author "Mohamed, Tarek"
Now showing items 1-2 of 2
-
Design, Synthesis and Biological Evaluation of 2,4-Disubstituted Pyrimidine Derivatives: Multifunctional Candidates as Potential Treatment Options for Alzheimer’s Disease
Mohamed, Tarek (University of Waterloo, 2011-08-30)Alzheimer’s disease (AD) is a highly complex and rapidly progressive neurodegenerative disorder characterized by the systemic collapse of cognitive function and formation of dense amyloid-β (Aβ) plaques and neurofibrillary ... -
Multi-Targeting Derivatives For Alzheimer’s Disease: Utilization of Quinazoline Ring Scaffolds
Mohamed, Tarek (University of Waterloo, 2016-08-30)The complex and multifaceted nature of Alzheimer’s pathology has significantly hindered the discovery and development of viable therapeutics, let alone the cause and initiation of the disease. Over the past century, what ...