Browsing Theses by Title
Now showing items 10850-10869 of 15565
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Peculiar Velocities and Large Scale Flows as Probes of Gravity, ΛCDM and the Growth of Structure over Cosmic Time
(University of Waterloo, 2012-09-28)Peculiar velocities are possibly the most powerful probes of very large-scale mass density fluctuations in the nearby Universe. When coupled with a density field they also can constrain the growth factor of the universe ... -
Pedestrian Activity Model for prioritizing investment – A case study of sidewalk snow clearing in the City of Waterloo
(University of Waterloo, 2019-01-07)This research emphasizes the needed integration for the empirical field of pedestrian modeling and the practical field of public works services. This is illustrated by focusing on the winter sidewalk maintenance delivery ... -
Pediatric Physiologically Based Pharmacokinetic (PBPK) Modeling to Advance Knowledge of Breastfeeding Infant Exposure to Maternal Medications
(University of Waterloo, 2023-05-04)While there are benefits of breastfeeding to the maternal-infant pair, mothers taking medication may decide not to breastfeed amid unclear risks of exposing the infant to the drug through milk. Uncertainty arises mainly ... -
Pedicle Screw Insertion Surgical Simulator
(University of Waterloo, 2018-02-16)Scoliosis is a sideway spinal deformity. If the curvature is measured to be more than 50 degrees, the patient can feel significant discomfort. In such cases, surgery is required to straighten the spine. Pedicle screw ... -
Peer Language Use and Criminal Decision-Making: An Experimental Study Testing Framing Effects of Peer Messages
(University of Waterloo, 2023-05-25)Criminal decision-making tends to occur in social contexts. There is evidence that the decision to commit a crime is often preceded by verbal communication, however, relatively little is known about the mechanisms through ... -
Peer-Based Intelligent Tutoring Systems: A Corpus-Oriented Approach
(University of Waterloo, 2012-05-11)In this thesis, we present an artificial intelligence approach for tutoring students in environments where there is a large repository of possible learning objects (e.g. texts, videos). In particular, we advocate that ... -
Pencil Light Transport
(University of Waterloo, 2005)Global illumination is an important area of computer graphics, having direct applications in architectural visualization, lighting design and entertainment. Indirect illumination effects such as soft shadows, color ... -
People know how diverse their music recommendations should be; why don’t we?
(University of Waterloo, 2021-02-17)While many researchers have proposed various ways of quantifying recommendation list diversity, these approaches have had little input from users on their own perceptions and preferences in seeking diversity. Through a ... -
The People's Cart "One Country, Two Systems; One Public Space, Two Ideologies; One Public Sphere, Two Perspectives"
(University of Waterloo, 2014-12-16)In 1842, China signed a treaty that leased Hong Kong to Great Britain for 99 years as a result of China’s loss in the Opium War and its trading of tea for opium. This agreement changed the fate and destiny of the Chinese ... -
People, Flour, Water, Salt: Bread and Community in Urban Public Space
(University of Waterloo, 2019-06-25)People, Flour, Water, Salt is a proposal for re-thinking the ways in which we connect to and learn from one another in urban public space. Bread is a staple food and cultural artifact, and its production exemplifies the ... -
Peptide Mediated siRNA Delivery: Physicochemical and in vitro Characterizations
(University of Waterloo, 2008-01-22)Short interfering RNAs (siRNAs) trigger RNA interference (RNAi) both in vitro and in vivo, where the expression of the encoded protein is silenced. Its potential use as a therapeutic agent is limited by its rapid enzymatic ... -
Peptide Sequencing with Deep Learning
(University of Waterloo, 2020-09-30)In shotgun proteomics, de novo peptide sequencing from tandem mass spectrometry data is the key technology for finding new peptide or protein sequences. It has successful applications in assembling monoclonal antibody ... -
Peptide-Driven Tri-Modal Gene Delivery Systems (PDTMG): Novel Versatile Peptide-Based Lipopolyplexes Incorporating Peptide-Functionalized Gemini Surfactants for Targeted Gene Therapy- Implementation of RGD Motifs as a Means for Endosomal Escape
(University of Waterloo, 2018-09-04)The development of non-viral gene delivery vectors is highly challenging and aims to provide a safe while cost-effective manufacturing alternative to viral vectors. Eleven novel gemini surfactants (G4-G14) were designed ... -
Peptide-Mediated Anticancer Drug Delivery
(University of Waterloo, 2009-08-21)An ideal drug delivery system should contain an appropriate therapeutic agent and biocompatible carrier. In this study, we investigated the ability of the all-complementary self-assembling peptide AC8 in stabilizing the ... -
Perceived Barriers to Exercise among Older Adults with MCI and Early Dementia
(University of Waterloo, 2017-09-08)Increasing evidence suggests that exercise can benefit physical and cognitive function among older adults with mild cognitive impairment (MCI) and early dementia (MCI/dementia). Unfortunately, many older adults with ... -
Perceived Emotional Synchrony in Virtual Watch Parties
(University of Waterloo, 2022-02-28)The appeal of many leisure activities emerges from “shared experience,” wherein participants feel an emotional synchrony with fellow participants. Essentially, participants’ emotions are enhanced by their awareness of and ... -
Perceived Risk of Tobacco Products among Adult Tobacco Users in Bangladesh and India
(University of Waterloo, 2014-10-27)There is considerable evidence demonstrating that smokers underestimate or minimize their own perceived risk of harm from smoking, and that smokers’ perceptions of risk play a key role in their behaviour, notably quitting. ... -
Perceived Stress, Physiological Stress, and Mental Health in Parents and Children
(University of Waterloo, 2021-09-23)Background: Elevated stress levels have been linked to a variety of health concerns, including mental disorders, making stress an important topic of research and clinical assessment. The human stress response involves the ... -
Perceived Susceptibility to Developing Cancer and Cancer Screening Behaviour: A Longitudinal Analysis of Alberta’s Tomorrow Project
(University of Waterloo, 2017-10-25)Background: Screening for cancer is a secondary prevention strategy that relies on early detection of disease. Screening is given to asymptomatic individuals who are at risk of developing cancer to identify and halt the ... -
Perceived Timing of Active Head Movements at Different Speeds
(University of Waterloo, 2018-06-11)The central nervous system must determine which sensory events occur at the same time. Actively moving the head corresponds with large changes in the relationship between the observer and the environment, sensorimotor ...