Browsing Theses by Subject "cytotoxicity"
Now showing items 1-3 of 3
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Characterization and evaluation of amphipathic, cationic peptides for small interfering RNA delivery
(University of Waterloo, 2015-06-19)RNA interference (RNAi) is a highly efficient and specific posttranscriptional gene silencing process, which can be triggered by small interfering RNA. The efficiency and specificity of this process makes siRNA a powerful ... -
Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products
(University of Waterloo, 2009-04-27)The utilization of in vitro tests with a tiered testing strategy for detection of mild ocular irritants can reduce the use of animals for testing, provide mechanistic data on toxic effects, and reduce the uncertainty ... -
Engineering of poly(2-oxazoline)s for a potential use in biomedical applications
(University of Waterloo, 2015-01-27)This PhD work is based on the design of poly(2-oxazoline) (POx) hydrogels and nanogels, by chemical or physical cross-linking, aimed to be used for biomedical applications. Nanogels were first prepared in dilute media and ...