Browsing Kinesiology and Health Sciences by Issue Date
Now showing items 41-60 of 465
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Hsp70 Protects Against Peroxynitrite-Induced Inactivation of SERCA2a by Preventing Protein Oxidation and Aggregation
(University of Waterloo, 2008-09-18)The purpose of this study was to examine the effects of exogenous peroxynitrite (ONOO-) on the cardiac isoform of the sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2a) and to determine if overexpression of heat shock ... -
Coordination of turning when standing and walking in healthy older adults and persons with Parkinson’s disease
(University of Waterloo, 2008-10-23)It is difficult to think of any activity that does not require some degree of turning. Despite the prevalence of turning in daily activities and the challenge it poses to mobility-impaired individuals such as those with ... -
Dynamic Control Strategies Used by ACL-Deficient Copers and Non-Copers during Stair Climbing
(University of Waterloo, 2008-10-23)Background: Osteoarthritis (OA), the most common form of arthritis, is a disorder that affects bi-articular synovial joints and is characterized as the focal loss of articular cartilage with changes to the subchondral and ... -
Effects of Aging in Pointing to Visible and Remembered Targets
(University of Waterloo, 2009-01-22)Most studies that have compared pointing to visible versus remembered targets have involved situations when both the limb and target are present (closed loop-target present), or when both the limb and target are occluded ... -
Developing a Non-Invasive Method to Monitor Cardiovascular Control during Orthostatic Challenge Considering the Limitation of the FinometerTM
(University of Waterloo, 2009-03-25)Sensations of dizziness or fainting (pre-syncope or syncope) on standing up from a lying or a seated position are usually associated with impaired blood pressure regulation leading to inadequate perfusion of the brain. The ... -
The Role of Heat Shock Protein 70 in Protecting Muscle Mechanical Function & SERCA Function in Human Skeletal Muscle
(University of Waterloo, 2009-04-23)Two studies were conducted to determine if Hsp70 is able to protect human skeletal muscle from muscle mechanical damage and alterations in SERCA activity associated with prolonged concentric exercise. In the first study, ... -
Establishing the Effect of Vibration and Postural Constraint Loading on the Progression of Intervertebral Disc Herniation
(University of Waterloo, 2009-06-19)Intervertebral disc herniations have been indicated as a possible injury development pathway due to occupational vibration exposures in seated postures through epidemiological investigations. Little experimental evidence ... -
Biomechanical Predictors of Functionally Induced Low Back Pain, Acute Response to Prolonged Standing Exposure, and Impact of a Stabilization-Based Clinical Exercise Intervention
(University of Waterloo, 2009-07-24)Purpose: Biomechanical differences between people with low back pain (LBP) and healthy controls have been shown previously. LBP has been associated with standing postures in occupational settings. A transient pain-generating ... -
Development of a novel mass-selected internal positive chemical ionization quadrupole ion trap mass spectrometry technique for the quantitative analysis of isotopic polyunsaturated fatty acids
(University of Waterloo, 2009-07-28)Analytical instrumentation for quantitative in vivo stable isotope metabolic studies has included gas chromatography-mass spectrometry (GC-MS) and gas chromatography-combustion-isotope ratio mass spectrometry (GC-C-IRMS). ... -
The Influence of the Tensile Material Properties of Single Annulus Fibrosus Lamellae and the Interlamellar Matrix Strength on Disc Herniation and Progression
(University of Waterloo, 2009-07-30)Low back pain is highly prevalent in the developed world, with 80% of the population being affected at some point in their lives. Herniation, a common injury to the intervertebral disc, is characterized as the posterior ... -
Investigating the efficacy of the NASA fluid loading protocol for astronauts: The role of hormonal blood volume regulation in orthostasis after bed rest
(University of Waterloo, 2009-08-05)Despite years of research, the role that hypovolemia plays in orthostatic intolerance after head down bed rest (BR) and spaceflight remains unclear. Additionally, the efficacy of oral saline countermeasures, employed in ... -
Endothelium-dependent vasomotor responses of hypertensive and type 2 diabetic rats: effects of sex, ageing, and therapeutic interventions
(University of Waterloo, 2009-08-26)Impaired endothelial vasomotor function is a hallmark of many chronic disease states, including essential hypertension and type 2 diabetes mellitus. Loss of the homeostatic role of the endothelium in large conduit arteries ... -
Postural motor learning and the effects of age on practice-related improvements in compensatory posture control
(University of Waterloo, 2009-08-27)The purpose of this thesis was to examine the capacity for acquisition and retention of practice-related improvements in compensatory posture control and the nature of postural motor learning among healthy young and older ... -
Treadmill Walking Capacity among Older Adults in Assisted Living Settings: A pilot, feasibility study
(University of Waterloo, 2009-08-28)Background: Decreased physical activity levels are an increasing concern, specifically for the aging population. Older adults (>65 years) are able to achieve health benefits from participating in a regular exercise program ... -
The effect of different manual task simulation methods on hand and forearm demand estimates
(University of Waterloo, 2009-08-28)The force exerted during manual tasks is a dominant risk factor for upper-limb musculoskeletal disorders. To identify tasks that may lead to fatigue over a shift, or increase the risk of injury, the demands placed on the ... -
Sensory information to motor cortices: Effects of motor execution in the upper-limb contralateral to sensory input.
(University of Waterloo, 2009-09-29)Performance of efficient and precise motor output requires proper planning of movement parameters as well as integration of sensory feedback. Peripheral sensory information is projected not only to parietal somatosensory ... -
Quantification and Evaluation of Physical Shoulder Exposures in Police Mobile Data Terminal Operators
(University of Waterloo, 2009-09-30)Mobile police officers perform many of their daily duties within vehicles. Combined workspace inflexibility and prolonged driving exposure creates a risk for developing musculoskeletal issues. Limited research exists that ... -
Examination of sex differences in quadriceps fatigability and Hsp70 content in response to intense intermittent isometric exercise
(University of Waterloo, 2009-09-30)The purpose of this study was to determine if there are sex differences in induced heat shock protein 70 (Hsp70) expression in human skeletal muscle under basal conditions and in response to intense intermittent isometric ... -
Cortical and behavioural adaptations induced by bimanual movement training: an electrophysiological study in the healthy population
(University of Waterloo, 2009-09-30)Bimanual movement training (BMT) of the upper extremity has been found to improve sensorimotor function of the stroke affected limb for some patients; however, the neurophysiological mechanism underlying behavioural ... -
Evaluation of polyunsaturated fatty acid uptake, distribution, and incorporation into specific muscle types
(University of Waterloo, 2009-10-01)Polyunsaturated fatty acids (PUFA) affect key cellular and physiological processes in the body ranging from cell signalling to inflammation. Compositional, dietary refinement and bioassay studies have shown strong associations ...