Browsing Mathematics (Faculty of) by Supervisor "Cook, Richard"
Now showing items 1-9 of 9
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Design and Analysis of Life History Studies Involving Incomplete Data
(University of Waterloo, 2022-04-26)Incomplete life history data can arise in study designs, coarsened observations, missing covariates, and unobserved latent processes. This thesis consists of three different projects developing statistical models and ... -
Failure Time Analysis with Discrete Marker Processes under Intermittent Observation
(University of Waterloo, 2021-07-28)Regression analysis for failure time data is often directed at studying the relationship between a time-dependent biomarker and failure. The Cox regression model and the associated partial likelihood on which inference ... -
Joint modeling, variable selection and multiply robust estimation in mediation analysis with multiple mediators
(University of Waterloo, 2024-01-10)This thesis explores topics in causal mediation analysis with multiple possibly related mediators. The goal of this thesis is to propose innovative methodologies for joint modeling of multiple uncausally related mediators, ... -
Marginal Causal Sub-Group Analysis with Incomplete Covariate Data
(University of Waterloo, 2019-01-11)Incomplete data arises frequently in health research studies designed to investigate the causal relationship between a treatment or exposure, and a response of interest. Statistical methods for conditional causal effect ... -
Mixture Models for Coarsened Multivariate Failure Time Data
(University of Waterloo, 2018-08-13)The aim of this thesis is to develop statistical methodology for the analysis of life history data under incomplete observation schemes and with latent features which must be accom- modated to ensure models provide a ... -
Modeling and Prediction of Disease Processes Subject to Intermittent Observation
(University of Waterloo, 2016-07-21)This thesis is concerned with statistical modeling and prediction of disease processes subject to intermittent observation. Times of disease progression are interval-censored when progression status is only known at a ... -
Statistical Models and Methods for Dependent Life History Processes
(University of Waterloo, 2018-11-28)This thesis deals with statistical issues in the analysis of complex life history processes which have characteristics of heterogeneity and dependence. We are motivated, in this thesis, by three specific types of ... -
Topics in Study Design and Analysis Involving Incomplete Data
(University of Waterloo, 2021-07-27)Incomplete data is a common occurrence in statistics with various types and mechanisms such that each can have a significant effect on statistical analysis and inference. This thesis tackles several statistical issues in ... -
Topics in the Design of Life History Studies
(University of Waterloo, 2018-08-20)Substantial investments are being made in health research to support the conduct of large cohort studies with the objective of improving understanding of the relationships between diverse features (e.g. exposure to toxins, ...