Browsing Science (Faculty of) by Title
Now showing items 179-198 of 3043
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Asymmetric Conjugate Addition of Boronates to N-Acylimines and β-Silyl-α,β-unsaturated Ketones Catalyzed by 3,3'-Disubstituted Binaphthols
(University of Waterloo, 2009-01-23)In order to extend the scope of asymmetric conjugate alkenylation catalyzed by 3,3′-disubstituted binaphthols, two classes of compounds were examined. Asymmetric 1,4-addition of alkenylboronates onto N-acylimines was ... -
Asymmetric Conjugate Additions of Boronates to α,β-Unsaturated Trifluoromethyl Ketones and Strategies Towards Asymmetric Conjugate Additions of N-Boc-Pyrrole Boronic Acid
(University of Waterloo, 2016-08-24)An important class of organic molecules are those that contain fluorine. Fluorinated molecules have found widespread use in medicinal chemistry, as well as in agrochemicals. This is due to the ability of fluorine to act ... -
Asymmetric soft-hard colloidal mixtures: osmotic effects, glassy states and rheology
(American Institute of Physics, 2017-09-06)Whereas mixtures of colloids and non-adsorbing polymers have been studied in great detail in the last two decades, binary colloidal mixtures have not received much attention. Yet, fragmental evidence from asymmetric mixtures ... -
Asymmetric Synthesis using 3,3'-Disubstituted Binaphthol-modified Boronates
(University of Waterloo, 2006)A number of 3,3'-disubstituted binaphthol-modified allylboronates (<strong>2. 42a-m</strong>) were prepared from the reaction between triallylborane and the corresponding 3,3'-disubstituted binaphthols. These chiral ... -
At the Corner of Space and Time
(University of Waterloo, 2019-12-09)We perform a rigorous piecewise-flat discretization of classical general relativity in the first-order formulation, in both 2+1 and 3+1 dimensions, carefully keeping track of curvature and torsion via holonomies. We show ... -
Atmospheric acidification of mineral aerosols: a source of bioavailable phosphorus for the oceans
(European Geosciences Union, 2011-07-01)Primary productivity of continental and marine ecosystems is often limited or co-limited by phosphorus. Deposition of atmospheric aerosols provides the major external source of phosphorus to marine surface waters. However, ... -
Atomic force microscopy analysis of the effect of plasma treatment on gas permeable contact lens surface topography
(Elsevier, 2019-02-23)Purpose: Using atomic force microscopy (AFM) to investigate anterior surface topography (AST) in worn and unworn, plasma surface-treated (PST) and untreated (UT) gas permeable (GP) lenses, and influence of surface topography ... -
Atomic force microscopy and Langmuir–Blodgett monolayer technique to assess contact lens deposits and human meibum extracts
(Elsevier, 2015-07)Purpose: The purpose of this exploratory study was to investigate the differences in meibomian gland secretions, contact lens (CL) lipid extracts, and CL surface topography between participants with and without meibomian ... -
Atomic Force Microscopy Study of Model Lipid Monolayers
(University of Waterloo, 2012-09-26)Alzheimer's Disease (AD) is a neurodegenerative disorder that is prevalent among the elderly population. Aß protein has been heavily implicated in the pathogenesis of AD. This protein in its fibrillar form is a major ... -
Atomic shell structure from an orbital-free-related density-functional-theory Pauli potential
(American Physical Society, 2020-07)Polymer self-consistent field theory techniques are used to find radial electron densities and total binding energies for isolated atoms. Quantum particles are modeled as Gaussian threads with ring-polymer architecture in ... -
Atomic Shell Structure in a Ring Polymer Formulation of Orbital-Free Density Functional Theory
(University of Waterloo, 2022-08-18)An alternative approach to orbital-free density functional theory based on self-consistent field theory for ring polymers is proposed and applied to isolated atoms on the periodic table in their ground-state. Using a ... -
Attaching DNA to Nanoceria: Regulating Oxidase Activity and Fluorescence Quenching
(American Chemical Society, 2013-08-14)Cerium oxide nanoparticles (nanoceria) have recently emerged as a nanozyme with oxidase activity. In this work, we present a few important interfacial properties of nanoceria. First, the surface charge of nanoceria can be ... -
Attentional Factors Underlying Binocular Vision Loss in Amblyopia
(University of Waterloo, 2022-01-13)Amblyopia is a neurodevelopmental disorder of vision that results from abnormal visual experience during early development. In addition to significant vision loss in one eye, individuals with amblyopia experience binocular ... -
Augmenting Basin-Hopping With Techniques From Unsupervised Machine Learning: Applications in Spectroscopy and Ion Mobility
(Frontiers, 2019-08-07)Evolutionary algorithms such as the basin-hopping (BH) algorithm have proven to be useful for difficult non-linear optimization problems with multiple modalities and variables. Applications of these algorithms range from ... -
Augmenting Quantum Mechanics with Artificial Intelligence
(University of Waterloo, 2018-12-04)The simulation of quantum matter with classical hardware plays a central role in the discovery and development of quantum many-body systems, with far-reaching implications in condensed matter physics and quantum technologies. ... -
Automated Cataract Grading using Smartphone Images
(University of Waterloo, 2021-02-02)A cataract is an age-related eye disease and is one of the leading ophthalmological public health problems in developed and developing countries. Early detection of cataracts is necessary to preserve sight and prevent the ... -
Automated High-throughput Analysis of Multi-class Multi-residue Pharmaceutical Drugs in Animal Tissue Using Solid Phase Microextraction
(University of Waterloo, 2020-05-06)The use of veterinary pharmaceuticals in today´s intensive farming of food-producing animals is essential for the humane treatment of animals and as well as for the prevention of outbreaks of infectious diseases. Improper ... -
Automated Segmentation of Retinal Optical Coherence Tomography Images
(University of Waterloo, 2018-08-21)Aim. Optical Coherence Tomography (OCT) is a fast and non-invasive medical imaging technique which helps in the investigation of each individual retinal layer structure. For early detection of retinal diseases and the study ... -
Automatic estimation of aquifer parameters using long-term water supply pumping and injection records
(Springer, 2016-09-01)Analyses are presented of long-term hydrographs perturbed by variable pumping/injection events in a confined aquifer at a municipal water-supply well field in the Region of Waterloo, Ontario (Canada). Such records are ... -
The automatic use of capillary isoelectric focusing with whole column imaging detection for carbamazepine binding to human serum albumin
(Elsevier, 2017-08-05)The binding of the anticonvulsant drug carbamazepine (CBZ) to human serum albumin, both without (dHSA) and in the presence of fatty acids (HSA) was studied in real time by capillary isoelectric focusing with whole column ...