Browsing Science (Faculty of) by Title
Now showing items 279-298 of 3044
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Calibration of the Flory-Huggins Interaction Parameter in Field-Theoretic Simulations
(2019)Field-theoretic simulations (FTS) offer a versatile method of dealing with complicated block copolymer systems, but unfortunately they struggle to cope with the level of fluctuations typical of experiments. Although the ... -
Calmodulin as a universal regulator of voltage gated calcium channels
(University of Waterloo, 2014-05-22)Calmodulin (CaM) is a ubiquitous calcium-binding protein responsible for the binding and activation of a vast number of enzymes and signaling pathways. It contains two lobes that bind two calcium ions each, separated by a ... -
Calmodulin Binding and Activation of Mammalian Nitric Oxide Synthases
(University of Waterloo, 2008-05-12)Calmodulin (CaM) is a ubiquitous cytosolic Ca2+-binding protein involved in the binding and regulation of more than three-hundred intracellular target proteins. CaM consists of two globular domains joined by a central ... -
Calmodulin regulates Cav3 T-type channels at their gating brake
(American Society for Biochemistry and Molecular Biology, 2017-12-08)Calcium (Cav1 and Cav2) and sodium channels possess homologous CaM-binding motifs, known as IQ motifs in their C termini, which associate with calmodulin (CaM), a universal calcium sensor. Cav3 T-type channels, which serve ... -
Can current models of accommodation and vergence predict accommodative behavior in myopic children?
(Elsevier, 2014-08)Investigations into the progression of myopia in children have long considered the role of accommodation as a cause and solution. Myopic children show high levels of accommodative adaptation, coupled with accommodative lag ... -
Can kynurenic acid cause myelin loss in chicken optic nerves?
(University of Waterloo, 2017-09-27)Kynurenic acid (KYNA) is one of many kynurenine intermediate products in the tryptophan metabolism pathway and has been shown to have neuro-activity. Previous work revealed that prolonged infusion of a high dose of KYNA ... -
Can Lensing Measure The Shape Of Dark Matter Halos?
(University of Waterloo, 2012-09-27)The aim of this project was to explore the shapes of dark matter halos using high resolution N-body simulations. One of the main aspects explored was how well the shape can be measured through weak lensing. To explore this, ... -
Canonical Structure and Conservation Laws of General Relativity on Null Surfaces and at Null Infinity
(University of Waterloo, 2021-01-12)The first part of this thesis addresses the canonical structure of general relativity on generic null surfaces. The pre-symplectic potential of metric general relativity, evaluated on a null surface, is decomposed into ... -
Capturing Plant Metabolome with Direct-Immersion in Vivo Solid Phase Microextraction of Plant Tissues
(American Chemical Society, 2015-12-15)For the first time, an in vivo sampling mode of direct immersion–solid phase microextraction (DI-SPME) was employed to capture the metabolome of living plant specimens, using apple (Malus × domestica Borkh.) as a model ... -
The carbon and nitrogen composition of suspended particulate matter in Lake Erie, selected tributaries, and its outflow
(University of Waterloo, 2005)Since their introduction to Lake Erie, dreissenid mussels may have reengineered the cycling of nutrients in the lake so that the nearshore benthic community intercepts, retains, and recycles greater quantities of nutrients. ... -
Carbon Cycling in a Glacier Ice Meltwater Impacted Freshwater System of the Canadian High Arctic: Biogeochemical Processes of the Lake Hazen Watershed
(University of Waterloo, 2022-03-23)Accelerated glacier ice mass loss and intensified meltwater fluxes are among principal vectors of change affecting northern latitudes in a warming climate. Aquatic systems impacted by glacier ice meltwater are vulnerable ... -
Carbon Metabolism and Desiccation Tolerance in the Nitrogen-Fixing Rhizobia Bradyrhizobium japonicum and Sinorhizobium meliloti
(University of Waterloo, 2009-04-22)Most members of the Rhizobiaceae possess single copies of the poly-3-hydroxybutyrate biosynthesis genes, phbA, phbB and phbC. Analysis of the genome sequence of Bradyrhizobium japonicum reveals the presence of five homologues ... -
Carbon Nanomaterials for Nanofluidic and Membrane Applications
(University of Waterloo, 2014-12-11)The successful fabrication and characterization of carbon nanomaterials as potential next generation materials for nanofluidic and membrane applications was demonstrated by this work. Ion transport through graphene oxide ... -
Carbon nanotube electromechanical systems: Non-linear dynamics and self-oscillation
(University of Waterloo, 2020-05-13)This thesis is motivated by the many sensing applications of carbon nanotube (CNT) nano-electromechanical systems (NEMS), both previous state-of-the-art demonstrations and proposed new uses. This research is particularly ... -
Carbon Nanotubes as Versatile Devices for Detoxification and Cellular Entry
(University of Waterloo, 2012-10-30)The ability to bypass most cellular barriers to gain access to intracellular compartments has great potential in cell biology. The possibilities range from efficient delivery of macromolecules such as plasmids to small ... -
Cardiolipin Prevents Membrane Translocation and Permeabilization by Daptomycin
(American Society for Biochemistry and Molecular Biology, 2014-04-25)Daptomycin is an acidic lipopeptide antibiotic that, in the presence of calcium, forms oligomeric pores on membranes containing phosphatidylglycerol. It is clinically used against various Gram-positive bacteria such as ... -
Casting Shadow on the Photocatalytic Activity of Plasmonic Antimony Doped Tin Oxide Nanoparticles in Degrading Rhodamine 590
(University of Waterloo, 2018-06-04)Increasing the feasibility of water purification systems at the manufacturing, technical and material engineering level is an urgent matter that is of global interest. Concerning materials engineering for water purification ... -
The Catalytic Intramolecular Friedel-Crafts Acylation of Meldrum's Acid Derivatives and The Total Synthesis of Taiwaniaquinol B
(University of Waterloo, 2005)The intramolecular Friedel-Crafts acylation of aromatics with Meldrum?s acid derivatives catalyzed by metal trifluoromethanesulfonates and other Lewis acids is reported. Meldrum?s acids are easily prepared, functionalized, ... -
Catalytic Nucleic Acids: Biochemistry, Chemical Biology, Biosensors, and Nanotechnology
(Elsevier, 2020-01)Since the initial discovery of ribozymes in the early 1980s, catalytic nucleic acids have been used in different areas. Compared with protein enzymes, catalytic nucleic acids are programmable in structure, easy to modify, ... -
Catalytic Potential and Ligand Binding Properties of the Malachite Green RNA Aptamer
(University of Waterloo, 2008-09-18)The malachite green aptamer was originally engineered for binding specificity to malachite green (MG). The environment inside the aptamer’s electronegative binding pocket was previously harnessed to catalyze an ester ...