Browsing Science (Faculty of) by Title
Now showing items 319-338 of 3049
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Characterisation and Analysis of Catastrophic Landslides and Related Processes using Digital Topographic Data
(University of Waterloo, 2014-08-14)This thesis represents a large body of work that seeks to describe, quantify, and simulate the behaviour of large rock slope failures (> 1 Mm³), in the form of landslides and rock avalanches, and their secondary processes, ... -
Characterisation and Optimization of Ultrashort Laser Pulses
(University of Waterloo, 2003)The ultrafast optical regime is defined, as it applies to laser pulses, along with a brief introduction to pulse generation and characterisation technologies. A more extensive description of our particular amplified ... -
Characterising changes in adhesion and enzyme activity related to drug resistance in colon cancer cells
(University of Waterloo, 2018-12-21)Metastatic colorectal cancer is often fatal, and drug resistance to chemotherapeutic agents is one of the primary contributing factors to this lethality. Drug resistance arises from exposure to chemotherapies, and it can ... -
Characterization and Analysis of the Microbiota of Bangia atropurpurea and other Freshwater and Marine Algae in North America
(University of Waterloo, 2021-09-14)Algae are a diverse polyphyletic group of photosynthetic organisms that contribute to forming rich ecosystems within marine and freshwater habitats. Many factors contribute to algal function and growth, such as the chemistry ... -
Characterization and Control in Large Hilbert spaces.
(University of Waterloo, 2008-12-03)Computational devices built on and exploiting quantum phenomena have the potential to revolutionize our understanding of computational complexity by being able to solve certain problems faster than the best known classical ... -
Characterization and expression patterns of five Winter Rye β-1,3-endoglucanases and their role in cold acclimation
(University of Waterloo, 2007-01-23)Winter rye produces ice-modifying antifreeze proteins upon cold treatment. Two of these antifreeze proteins are members of the large, highly conserved, β-1,3-endoglucanase family. This project was designed to identify ... -
Characterization and Genetic Manipulation of D-cysteine Desulfhydrase from Solanum lycopersicum
(University of Waterloo, 2008-05-15)Progress in DNA sequencing of plant genomes has revealed that, in addition to microorganisms, a number of plants contain genes which share similarity to microbial 1-aminocyclopropane-1-carboxylate (ACC) deaminases. ACC ... -
Characterization of Active Cellulolytic Consortia from Arctic Tundra
(University of Waterloo, 2011-05-20)The consortia of microorganisms responsible for the hydrolysis of cellulose in situ are at present poorly characterized. Nonetheless, the importance of these communities is underscored by their capacity for converting ... -
CHARACTERIZATION OF AHR SIGNALING AND THE IMPACT OF POLYCHLORINATED BIPHENYLS ON THE ADAPTIVE RESPONSES TO STRESS IN FISH
(University of Waterloo, 2007-09-13)Persistent organic pollutants (POPs), including polychlorinated biphenyls (PCBs) are widespread in aquatic systems. These toxicants bioaccumulate in the tissues of aquatic organisms, especially fish as they occupy a position ... -
Characterization of Alcohol Dehydrogenases from Hyperthermus butylicus
(University of Waterloo, 2016-01-22)Hyperthermophiles grow optimally at 80 oC and above, and many of them use carbohydrates and peptides for their growth. Hyperthermus butylicus is a peptide-fermenting hyperthermophilic archaeon producing 1-butanol as an ... -
Characterization of Bacteriophage λ Displaying Epidermal Growth Factor in the Uptake, Infiltration and Formation of HT29 Spheroids
(University of Waterloo, 2019-07-31)Solid tumours are characterized by a complex structure comprised of extracellular matrix, neoplastic cells and stromal cells, each presenting a barrier to conventional anticancer chemotherapy as well as carrier-mediated ... -
A Characterization of Bromine and Chlorine Stable Isotopes in the Sand Hills Region of Nebraska, USA
(University of Waterloo, 2015-09-21)Saline lakes and salt flats are capable of releasing a significant flux of reactive bromine into the atmosphere, a compound which is 45-70 times more efficient at ozone destruction than chlorine (Eggenkamp, 2014; Risacher ... -
Characterization of Cadmium-Induced BiP Accumulation in Xenopus laevis A6 Kidney Epithelial Cells
(University of Waterloo, 2016-08-19)In vertebrates, cadmium exposure is found to cause respiratory, neurological and kidney disorders. At the cellular level, cadmium can damage or modify proteins resulting in the production of toxic protein aggregates. The ... -
The characterization of checkpoint kinase 2 in Oncorhynchus mykiss: Tissue specific expression suggests biomarker potential
(University of Waterloo, 2007-09-05)Chk2 is a cell cycle checkpoint kinase that is essential for initiating the DNA damage response in the presence of genetic damage. Its role is highly conserved from budding yeast (where it is named Rad53) to humans. Very ... -
Characterization of counterion effects of gemini surfactants and in vitro studies of transfection efficiency for gene therapy in epithelial ovarian cancer.
(University of Waterloo, 2015-01-23)Gene therapy has emerged as a promising strategy for the treatment or prevention of many acquired or genetic diseases that are considered incurable at the present time. Although viral and non-viral vector approaches are ... -
Characterization of daptomycin oligomerization with perylene excimer fluorescence: Stoichiometric binding of phosphatidylglycerol triggers oligomer formation
(Elsevier, 2012-03)Daptomycin is a lipopeptide antibiotic that binds to and depolarizes bacterial cell membranes. Its antibacterial activity requires calcium and correlates with the content of phosphatidylglycerol in the target membrane. ... -
The characterization of Dbf4 interactions and roles in genome replication and stability in Saccharomyces cerevisiae
(University of Waterloo, 2020-03-05)Dbf4-dependent kinase (DDK) is a complex composed of the Cdc7 kinase and its regulatory subunit, Dbf4. Initiation of eukaryotic DNA replication requires phosphorylation of Mcm2-7 helicase by DDK. Due to its essential role ... -
Characterization of Dbf4 structure and function in Saccharomyces cerevisiae DNA replication and checkpoint responses.
(University of Waterloo, 2014-02-21)The Dbf4/Cdc7 kinase complex is required for the initiation of DNA replication and promotes this by acting upon members of the Mcm2-7 helicase. In addition to its role in replication, Dbf4/Cdc7 is a target of the S-phase ... -
Characterization of Detector and Electron Source for Inverse Photoemission Spectrometer
(University of Waterloo, 2023-02-17)The inverse photo-emission spectroscopy (IPES) is a powerful tool to probe the unoccupied energy states of materials, such the surface states of metals or the unoccupied states of high temperature superconductors. IPES ... -
Characterization of Dissolved Organic Matter and Reduced Sulfur in Coastal Marine and Estuarine Environments: Implications for Protective Effects on Acute Copper Toxicity
(University of Waterloo, 2009-05-13)Copper-induced toxicity in aqueous systems depends on its speciation and bioavailability. Dissolved organic matter (DOM) and reduced sulfur species can complex copper, influencing speciation and decreasing bioavailability. ...