Browsing Science (Faculty of) by Title
Now showing items 339-358 of 3049
-
Characterization of Eukaryotic Translation Initiation Factor 5A isoforms (eIF-5A1 & eIF-5A2) using human cell lines as a model system
(University of Waterloo, 2006)Eukaryotic translation initiation factor 5A (eIF-5A) is the only known cellular protein that contains the post-translationally derived amino acid, hypusine. Initially, eIF-5A was named as a translation initiation factor ... -
Characterization of Eukaryotic Translation Initiation Factor 5A-2 (eIF5A-2) in <i>Arabidopsis thaliana</i>: Effects of Wounding and Pathogen Attack
(University of Waterloo, 2004)Plants respond to wounding and pathogen ingress by synthesizing defence proteins that facilitate wound healing, cell death or provide protection against further pathogen attack. The accumulation of these proteins is ... -
Characterization of gate oxides and microwave resonators for silicon spin qubit devices
(University of Waterloo, 2022-01-21)Silicon quantum dots present themselves as a promising implementation for quantum information processing due to the fact that they possess a small chip foot-print, yield high coherence times and are able to leverage the ... -
Characterization of gemini nanoparticle assembly by fluorescence correlation spectroscopy
(University of Waterloo, 2014-01-23)Research in the field of non-viral gene delivery has demonstrated that a deeper understanding of the fundamental processes of nanoparticle assembly is required in order to improve their efficacy. While gemini nanoparticles ... -
Characterization of Genes involved In Development and Senescence
(University of Waterloo, 2006)Plant development is complex and highly regulated. Tens of thousands of genes have been sequenced for the model plant <em>Arabidopsis thaliana</em>, yet few have been functionally annotated and characterized. This ... -
Characterization of glucose oxidation by gold nanoparticles using nanoceria
(Elsevier, 2014-04-30)Gold nanoparticles (AuNPs) can oxidize glucose, producing hydrogen peroxide and gluconic acid, which are the same products as those generated by glucose oxidase (GOx). In this regard, AuNPs are a nanozyme. Herein, a new ... -
Characterization of High-PGE Low-Sulphur Mineralization at the Marathon PGE-Cu Deposit, Ontario
(University of Waterloo, 2013-03-13)The Marathon PGM-Cu deposit is hosted by the Coldwell alkaline complex, which consists predominantly of gabbro and syenite and was emplaced at 1108 Ma as part of the Mid-Continent Rift System. Mineralization at the Marathon ... -
Characterization of HSP47 Expression in <i>Xenopus Laevis</i> Cell Culture and Embryos
(University of Waterloo, 2005)The heat shock or stress response is a transient response to stressful stimuli that protects vital cellular proteins from damage and irreversible aggregation. Heat shock proteins (Hsps) are molecular chaperones that ... -
Characterization of Hydrophobically Modified Starch Nanoparticles by Pyrene Fluorescence
(University of Waterloo, 2017-01-25)Starch nanoparticles (SNPs) were hydrophobically modified with propionic (C3) and hexanoic (C6) anhydride via esterification. Different degrees of substitution (DS) of the hydroxyl groups of the SNPs were achieved by varying ... -
Characterization of iron- and zinc-containing alcohol dehydrogenases from anaerobic hyperthermophiles
(University of Waterloo, 2007-12-18)Hyperthermophiles are microorganisms that can grow at temperatures close to the boiling point of water or above. They are potential resources of thermostable enzymes including alcohol dehydrogenases (ADHs). Both Thermococcus ... -
Characterization of Langmuir-Blodgett Films by Electron Spin Resonance Spectroscopy
(University of Waterloo, 2020-01-15)Langmuir-Blodgett (LB) films built up with amphiphilic molecules have well-known optical, electrical and magnetic properties. For most applications, it is fundamentally important to understand the structure of the films. ... -
Characterization of Lipid Deposition on Contact Lenses
(University of Waterloo, 2017-08-30)The purpose of this thesis was to evaluate the influence of lipid deposition on silicone hydrogel contact lens materials and to construct an in vitro platform to further explore the effect of lipid interaction with contact ... -
Characterization of Mrc1 during Replication Initiation in Saccharomyces cerevisiae
(University of Waterloo, 2022-01-12)DNA replication is a highly specific process that is completed under the control of several factors, to ensure faithful duplication of the genome. Mrc1 (Claspin in mammalian cells) is a protein that is a part of a fork ... -
Characterization of novel FHA domain ligand binding motifs
(University of Waterloo, 2016-01-25)Rad53, a key checkpoint protein in Saccharomyces cerevisiae, has a central catalytic kinase domain as well as two forkhead-associated (FHA) domains, FHA1 and FHA2. Along with the extensively studied phosphothreonine binding ... -
Characterization of Novel Protease Flagellinolysin in Pseudoalteromonas tunicata
(University of Waterloo, 2024-01-03)Flagellinolysins are a family of novel enzymes that act both as structural flagellins and proteases. Although previously identified and shown to be both structurally integrated into filaments and proteolytically active, ... -
Characterization of Orc6 function following pre-replicative complex assembly in Saccharomyces cerevisiae
(University of Waterloo, 2008-10-22)Pre-replicative complex (pre-RC) components the origin recognition complex (ORC), Cdc6, and Cdt1, play key roles in the recruitment, and loading of the replicative helicase, the minichromosome maintenance complex (Mcm2-7), ... -
Characterization of p53 in rainbow trout cell lines
(University of Waterloo, 2010-09-27)The tumour suppressor protein p53 is a critical protein in the DNA damage checkpoint pathway. It acts as a transcription factor that is involved in initiating the apoptotic pathway; disruption of this pathway can lead to ... -
Characterization of PIBSI Dispersants and Their PIBSA Components by Pyrene Excimer Fluorescence
(University of Waterloo, 2020-12-18)Methods are introduced to characterize the products resulting from the coupling of a polyisobutylene terminated at one end with a succinic anhydride (PIBSA) and a polyamine to generate PIBSI products where the polyamine ... -
Characterization of Polysaccharides in Starch using Fluorescence Techniques
(University of Waterloo, 2020-09-25)Amylose and amylopectin, which are the two main constituents of starch, were characterized using the pyrene excimer fluorescence (PEF) technique. First, an amylose sample was randomly labeled with the dye pyrene to yield ... -
Characterization of Self-Assembling Quinoline- Based Foldamers by Fluorescence Anisotropy
(University of Waterloo, 2019-09-24)Foldamers represent a family of synthetic macromolecules which, like their biological counterparts, are able to adopt a well-defined conformation in solution. Oligoquinoline-carboxamides (Qn) are a group of foldamers that ...