Browsing Science (Faculty of) by Title
Now showing items 511-530 of 3045
-
Construction and Characterization of a Fine-Tuned Lytic Phage Display System
(University of Waterloo, 2014-08-15)Bacteriophage (phage) Lambda (λ) has played a key historic role in driving our current understanding of molecular genetics. The lytic nature of this bacterial virus along with the conformation of its wild-type capsid protein ... -
Construction and characterization of a hybrid bacteriophage gene delivery platform
(University of Waterloo, 2022-04-26)Bacteriophages, viruses that specifically infect bacteria, may be considered as structurally simplistic protein-based vehicles for ferrying nucleic acid cargo. Since phages cannot infect nor replicate within human cells, ... -
Construction and Characterization of a Robust in vivo Technology for the Production of Superior DNA Vectors for Gene Therapy and Vaccination
(University of Waterloo, 2013-09-27)Plasmid DNA (pDNA) vectors are the current conventional technology driving therapeutic gene transfer, whether for use toward mal/nonfunctional gene replacement, DNA vaccination, or production of therapeutic proteins in ... -
The construction and characterization of a synthetic SARS VLP comprised of betacoronavirus consensus sequence-encoded viral components
(University of Waterloo, 2022-12-22)In 2019, a novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged from Wuhan, China leading to the COVID-19 pandemic. Although there was an outbreak of severe acute respiratory syndrome ... -
CONSTRUCTION AND OPTIMIZATION OF A ssDNA VECTOR PRODUCTION SYSTEM FOR GENE THERAPY PLATFORM
(University of Waterloo, 2023-06-15)Viral capsid of Anellovirus and ssDNA reporter constructs carrying an anellovirus intergenic region were both produced separately in E. coli systems, purified and then mixed together in an in vitro system. At particular ... -
Construction of a Shielded Thermal Hall Measurement Device
(University of Waterloo, 2023-05-26)A shielded thermal Hall experimental setup is being constructed and is nearing completion. An existing conventional thermal conductivity experiment was retrofit to perform thermal Hall measurements, which included the ... -
Contact lens fitting characteristics and comfort with silicone hydrogel lenses
(University of Waterloo, 2012-02-24)Purpose To examine soft contact lens fitting characteristics using anterior segment imaging techniques and comfort. The specific aims of each chapter are as follows: Chapter 2: To calibrate the new ZEISS VisanteTM ... -
Contact lens physical properties and lipid deposition in a novel characterized artificial tear solution
(Molecular Vision, 2011-12-24)Purpose: To characterize various properties of a physiologically-relevant artificial tear solution (ATS) containing a range of tear film components within a complex salt solution, and to measure contact lens parameters and ... -
Contact Lenses and Tear Film Lipids.
(University of Waterloo, 2017-12-20)Introduction Lipids are essential tear components that aid the stability of the tear film (TF) to protect it from excess evaporation. The composition, conformation, and function of TF lipids are jeopardized by external ... -
Contact Lenses for Ciprofloxacin Drug Delivery
(University of Waterloo, 2014-07-31)PURPOSE The purpose of this thesis was to evaluate the potential of contact lenses as ciprofloxacin drug delivery devices. METHODS Investigations into ciprofloxacin uptake and release characteristics, and the possibility ... -
Contaminants and Nutrients in Traditional Food Fishes in Kluane Lake, YT
(2016-06)The outcomes of a collaborative project led by the Kluane First Nation (KFN), in partnership with the Arctic Institute of Community-Based Research (AICBR), the University of Waterloo, and Western University, are presented ... -
Contemporary Diagnosis and Management of Dry Eye
(University of Waterloo, 2016-08-31)Introduction Dry eye (DE) disease is characterized by symptoms including, but not limited to, ocular stinging, burning, and tearing. The symptoms can range from being mildly irritating, to severely debilitating and ... -
Contextuality and Ontological Models: A Tale of Desire and Disappointment
(University of Waterloo, 2019-09-23)Since being defined by Kochen and Specker, and separately by Bell, contextuality has been proposed as one of the key phenomena that distinguishing quantum theory from classical theories. However, with the rise of quantum ... -
Continuous Tensor Networks, Conformal Field Theory and Holography
(University of Waterloo, 2020-07-23)Tensor network methods are playing a central role in multiple disciplines of modern quantum physics, such as condensed matter physics, quantum information and quantum gravity. Based on renormalization group (RG) ideas, ... -
Contrasting accessory mineral behavior in minimum-temperature melts: Empirical constraints from the Himalayan metamorphic core
(Elsevier, 2018-07-01)Medium-grained leucogranite in the Tama Kosi region of the Nepalese Himalayan Metamorphic Core yields a relatively narrow range of monazite 208Pb/232Th dates with a dominant population at ~21.0 Ma inferred to represent ... -
Contrasting physiological responses between invasive sea lamprey and non-target bluegill in response to acute lampricide exposure
(Elsevier, 2021-08-01)Control of invasive sea lamprey (Petromyzon marinus) in the Laurentian Great Lakes of North America uses lampricides, which consist of 3-trifluoromethyl-4-nitrophenol (TFM) and niclosamide. Lampricides are thought to inhibit ... -
Control and Readout of High-Dimensional Trapped Ion Qudits
(University of Waterloo, 2023-09-07)The trapped ion platform is one of the quantum computing platforms that is at the forefront for realizing large-scale quantum information processing, which is crucial for practically actualizing the advantages of quantum ... -
The Control of Fe and pH on the Photodegradation and Characterization of Dissolved Organic Matter in Small, Oligotrophic Canadian Shield Freshwaters
(University of Waterloo, 2017-05-19)Carbon is an essential building block for life and is involved in many biotic and abiotic processes. Thus it is imperative to have a comprehensive understanding of carbon cycling. Recent research has established that inland ... -
Control of Light-Matter Interactions in Classical and Quantum Optics
(University of Waterloo, 2018-01-12)In this thesis, we examined a series of techniques for controlling the interaction of light with matter that could be employed to optimize or to control physical phenomena in various potential applications. Some of these ... -
Control of mercury and methylmercury in contaminated sediments using biochars: A long-term microcosm study
(Elsevier, 2018-05-01)The effectiveness of activated carbon and four types of biochar, switchgrass (300 °C and 600 °C), poultry manure (600 °C), and oak (∼700 °C) with respect to mercury (Hg) and methylmercury (MeHg) control was assessed in ...