Browsing Science (Faculty of) by Title
Now showing items 639-658 of 3049
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Determining Molecular Physicochemical Properties Using Differential Mobility Spectrometry
(University of Waterloo, 2019-09-26)This thesis aims to explore the usage of differential mobility spectrometry (DMS) and quantum chemical calculations to separate and identify drug compounds, as well as the use of machine learning (ML) to predict physicochemical ... -
Determining the habitat occupancy of young of year Arctic Grayling (Thymallus arcticus) in sub-Arctic tundra streams while accounting for imperfect detection
(University of Waterloo, 2016-01-22)I developed multi-state, multi season occupancy models to determine how a number of interacting ecological variables influence the occurrence of young-of-year (YOY) Arctic Grayling (Thymallus arcticus) in nine streams on ... -
Determining the native and nonnative effects of myristoylation on the folding and switching of hisactophilin
(University of Waterloo, 2012-09-26)Myristoylation, the covalent linkage of a C14 saturated fatty acyl chain to the N-terminal glycine in a protein, plays an important role in reversible membrane and protein binding in cellular signaling by the modified ... -
Determining the relationships between forage use, climate and nutritional status of barren ground caribou, Rangifer tarandus groenlandicus, on Southampton Island, Nunavut, using stable isotopes analysis of d 13C and d 15N
(University of Waterloo, 2006)The caribou (Rangifer tarandus groenlandicus) on Southampton Island, Nunavut, Canada for the years 1998-2000 and 2004, 2005, were investigated using stable isotope analysis (SIA) of carbon (d 13C) and nitrogen (d 15N). ... -
Determining the Structures and Properties of Biologically-relevant Ions
(University of Waterloo, 2018-08-09)Gas phase studies of biologically relevant ions are increasing in popularity due to the possibility of high throughput analysis requiring minimum sample concentrations. This thesis explores the potential of differential ... -
Determining the subcellular localization of adenosine kinase and SAH hydrolase and their roles in adenosine metabolism
(University of Waterloo, 2007-01-23)Housekeeping enzymes are vital to the metabolism of all plant cells. Two such enzymes adenosine kinase (ADK) and S-adenosylhomocysteine (SAH) hydrolase share a similar function: both sustain S-adenosylmethionine-dependent ... -
Developing a Generalized Model for Neutron Diffraction with Quantum Information Theory
(University of Waterloo, 2022-08-31)Due to their high mass and neutral electric charge, neutrons are often used at low energies to probe small-scale structures or measure fundamental constants of nature. To design neutron optical elements for use in these ... -
Developing a Large-Scale, Programmable Trapped Ion Quantum Simulator with In Situ Mid-Circuit Measurement and Reset
(University of Waterloo, 2023-09-25)Quantum simulators are a valuable resource for studying complex many-body systems. With their ability to provide near-term advantages, analog quantum simulators show great promise. In this thesis, my aim is to describe the ... -
Developing a Method to Study Ground State Properties of Hydrogen Clusters
(University of Waterloo, 2014-05-05)This thesis presents the benchmarking and development of a method to study ground state properties of hydrogen clusters using molecular dynamics. Benchmark studies are performed on our Path Integral Molecular Dynamics code ... -
Developing a robust quantum simulator with trapped ions
(University of Waterloo, 2024-05-27)Trapped ion systems have experienced significant growth in recent years as their potential for excelling as quantum simulators has become recognized. Ions make an excellent qubit due to their long coherence times with ... -
Developing algorithms for the analysis of retinal Optical Coherence Tomography images
(University of Waterloo, 2018-09-04)Vision loss, with a prevalence loss greater than 42 million in the United States is one of the major challenges of today's health-care industry and medical science. Early detection of different retinal-related diseases ... -
Developing and characterizing a salmonid intestinal epithelial cell line for use in studies of inflammation in the fish gastrointestinal tract
(University of Waterloo, 2009-05-05)An intestinal cell line from rainbow trout, Oncorhynchus mykiss, was developed and challenged against several bioactive components. Primary cultures initiated from the distal segment produced the cell line, RTgutGC. ... -
Developing and refining the use of water isotope tracer in hydrology and paleohydrology
(University of Waterloo, 2008-08-27)This thesis investigates stable isotope signals (i.e. δ18O and δ2H) in various information carriers such as lake water and lacustrine sediments, aiming to develop and refine the use of isotope tracers in hydrology and ... -
Developing Novel Synthetic Methodologies Using Hypervalent Iodine(III) Reagents and Diazonium- or Iodonium Ylides
(University of Waterloo, 2018-02-14)Hypervalent iodine compounds have been established as useful reagents in synthetic chemistry due to their ease of handling and wide range of chemical reactivity under mild reaction conditions. Reported within are studies ... -
Developing pre-industrial baselines from floodplain lake sediment cores to quantify the extent of metals pollution within the Alberta Oil Sands Region
(University of Waterloo, 2018-11-28)Oil sands mining operations began in 1967, but the onset of a monitoring program to assess water and sediment quality in the Athabasca River watershed began 30 years later. Consequently, no knowledge of pre-industrial, ... -
Developing the Hydrologic Model of the Laurel Creek Watershed Including the Water Infrastructure
(University of Waterloo, 2016-01-22)Continued growth of the Canadian economy has led to an increased population, which resulted in the progressive urbanization of Canada’s watersheds. Additionally, as infrastructure ages, an increasing percentage of drinking ... -
Developing theoretical and experimental tools for a hybrid quantum simulator based on trapped ions
(University of Waterloo, 2018-09-05)Quantum simulation is the process of using a highly controllable quantum system to simulate another less controllable system. Quantum simulation can provide insights into the properties and dynamics of complex many-body ... -
Developing Virtual Field Experiences to Promote Student Learning and Bridge Knowledge Gaps between the Classroom and the Field
(University of Waterloo, 2021-05-01)In 2020, a specific type of Virtual Reality (VR), Virtual Field Experiences (VFE), was identified as a proof-of-concept for positively contributing to student learning by the University of Waterloo's Department of Earth ... -
Development and analysis of molecular methods for functional metagenomics of the human gut microbiome
(University of Waterloo, 2016-03-21)Interest in the human microbiome has risen quickly in recent years as the microbes that live in and on our body have been implicated in a growing number of human health and disease states. This interest has been supported ... -
Development and Application of a Consumable-Free Modulator for Comprehensive Two-Dimensional Gas Chromatography
(University of Waterloo, 2024-02-16)Comprehensive two-dimensional gas chromatography (GC×GC), is a separation method recognized as offering far greater peak capacity than conventional one-dimensional separations. Today, the most frequently used GC×GC systems ...