Science (Faculty of): Recent submissions
Now showing items 1-20 of 3037
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USER EXPERIENCE WITH MEDICATION ADHERENCE TECHNOLOGY: DETERMINING USABILITY BY CAPABILITIES
(University of Waterloo, 2024-05-27)Background: As populations worldwide grow older, the prevalence of chronic conditions and the complexity of managing multiple medications significantly increase. This challenge is further complicated by a range of barriers ... -
Developing a robust quantum simulator with trapped ions
(University of Waterloo, 2024-05-27)Trapped ion systems have experienced significant growth in recent years as their potential for excelling as quantum simulators has become recognized. Ions make an excellent qubit due to their long coherence times with ... -
The Development and Evaluation of Next-Generation Metallic Nanomedicines for Oncology
(University of Waterloo, 2024-05-27)Nanoparticles (NPs) are ultrasmall objects with profound applications in research, industry, and medicine. Next-generation nanomedicines, such as gold, hafnium, iron, and copper nanoparticles, are particularly interesting ... -
Random State Production for Quantum Key Distribution using Weak Coherent Pulse Source
(University of Waterloo, 2024-05-27)This thesis addresses two challenges involved in the culmination of the Quantum En- crYption and Science Satellite mission. This mission aims to demonstrate quantum key distribution (QKD) in space. The first part of the ... -
A Curiosity Driven Exploration of Hypervalent Iodine(III) Reagents
(University of Waterloo, 2024-05-27)Hypervalent iodine (HVI) reagents have established themselves in the literature as reagents with diverse reactivity and utility in many different transformations. Their unique bonding structure often leads to divergent ... -
Programmatic Representation of Quantum Many Body Systems
(University of Waterloo, 2024-05-23)The problem of simulating quantum many-body systems is fundamental in condensed matter physics, quantum computing, and quantum chemistry. The exact simulation of quantum many-body systems is generally intractable on classical ... -
Exploring Ruthenium Nanoparticles Geometric Complexity to Boost Kellogg Advanced Ammonia Process Through Confinement Effect
(University of Waterloo, 2024-05-23)Ammonia consumption is expected to increase in the future due to its use as a zero-carbon fuel and as a material for hydrogen storage and shipping. Among all single metal catalysts, ruthenium has the highest catalytic ... -
New method to improve the diagnostic utility of OCTA images in retinal disease
(University of Waterloo, 2024-05-23)Purpose: Diagnosing medical images necessitates years of experience to ensure accurate diagnoses. However, the current workforce available for this task falls significantly short compared to the volume of images requiring ... -
Towards the Development of a Prototype Ion Mobility Spectrometer
(University of Waterloo, 2024-05-22)Ion mobility spectrometry (IMS) is an analytical technique that separates ions in the gas-phase based on differences in their mobility under the influence of an electric field. In traditional drift-tube IMS systems, an ... -
Advancements in ThermOcular image processing algorithms for precise ocular surface temperature analysis
(University of Waterloo, 2024-05-22)In recent advancements in the field of Ocular Surface Temperature (OST) measurement, this thesis presents significant enhancements to the ThermOcular system, primarily focusing on its application in real-world clinical and ... -
Trapping of Ba+ using an Autoionizing Resonance and Construction of an Academic Ba+ Testbed
(University of Waterloo, 2024-05-21)Trapped ions are at the forefront of the quantum information processing field. This platform has demonstrated some of the highest native gate fidelities, in addition to offering fully connected qubits with incredibly long ... -
Design and Implementation of an Experimental Setup for Entanglement Harvesting
(University of Waterloo, 2024-05-17)Relativistic quantum information is an emerging field of study at the interface of relativity and quantum theories. One key result is the prediction of extracting entanglement from quantum fields known as “entanglement ... -
Line-Field Spectral Domain Optical Coherence Tomography: Design and Biomedical Applications
(University of Waterloo, 2024-05-10)Corneal diseases such as keratoconus and Fuchs' dystrophy lead to the dysfunction of the cornea, which can result in vision loss. Early-stage detection at the cellular level provides the opportunity for treatment that slows ... -
Differential Gene Expression Analysis using Resampling
(University of Waterloo, 2024-05-09)The primary objective in high-throughput sequencing is to identify differentially expressed genes, which provides substantial information of gene expression and regulation. A persistent challenge in this field is the bias ... -
Metatranscriptomic analysis of pediatric acute sinusitis: pathogen detection and host response profiling
(University of Waterloo, 2024-05-08)Acute sinusitis (AS) is the fifth leading cause of antibiotic prescriptions in children. Distinguishing bacterial AS from common viral upper respiratory infections in children is crucial to prevent unnecessary antibiotic ... -
Computational modeling of bacterial chromosome organization: macromolecular crowding, chain heterogeneity, and chain cross-linking
(University of Waterloo, 2024-04-30)Chromosome organization is integral to life, as it plays a pivotal role in maintaining the integrity and functionality of genomic materials, as well as facilitating the transcription, replication, and transmission of genetic ... -
The Effect of Freezing on the Elution of PVA from Contact Lenses
(University of Waterloo, 2024-04-30)Contact lenses are widely used, with over 140 million wearers globally. Wearing contact lenses can cause symptoms of discomfort and dryness, which affect nearly half of all wearers. To address this concern, this thesis ... -
Synthesis of Deuterated Benzene for a Circular Deuterium Economy
(University of Waterloo, 2024-04-30)Deuterium is an important natural isotope; its unique properties can impart significant effects on molecules with emerging applications across electronics and medicinal industries. Aromatic hydrocarbons or arenes are one ... -
Advancing Linear-Scaling Techniques in Computation of Exchange Matrices in Mean-Field and Cluster-in-Molecule Calculations
(University of Waterloo, 2024-04-30)Quantum chemistry faces ongoing challenges in developing methods that combine efficiency with accuracy, especially for large molecular systems. The Cluster-in-Molecule (CiM) technique, integrated with Coupled Cluster theory ... -
Pyrene Excimer Formation: A Tool to Study Macromolecular Conformations in Solution
(University of Waterloo, 2024-04-26)The current view for fluorescence collisional quenching (FCQ) experiments is that no quantitative information can be retrieved from macromolecules containing more than a single dye-quencher pair attached at two specific ...