Browsing Biology by Issue Date
Now showing items 41-60 of 599
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The characterization of checkpoint kinase 2 in Oncorhynchus mykiss: Tissue specific expression suggests biomarker potential
(University of Waterloo, 2007-09-05)Chk2 is a cell cycle checkpoint kinase that is essential for initiating the DNA damage response in the presence of genetic damage. Its role is highly conserved from budding yeast (where it is named Rad53) to humans. Very ... -
Investigation of Flavoproteins Involved in the Metabolism of Anaerobic Hyperthermophilic Microorganisms
(University of Waterloo, 2007-09-12)It was estimated that more than one hundred open reading frames in Pyrococcus furiosus and Thermotoga maritima could encode flavoproteins based on the results of motif search and comparison of genomic annotation to the ... -
CHARACTERIZATION OF AHR SIGNALING AND THE IMPACT OF POLYCHLORINATED BIPHENYLS ON THE ADAPTIVE RESPONSES TO STRESS IN FISH
(University of Waterloo, 2007-09-13)Persistent organic pollutants (POPs), including polychlorinated biphenyls (PCBs) are widespread in aquatic systems. These toxicants bioaccumulate in the tissues of aquatic organisms, especially fish as they occupy a position ... -
Characterization of the pro-apoptotic function of eIF5A in human cancer cell lines
(University of Waterloo, 2007-09-18)Eukaryotic translation initiation factor 5A (eIF5A) is the only known protein containing the unique amino acid, hypusine. eIF5A is present in all eukaryotic cells and is highly conserved, but its function is not well ... -
Studies of DNA methylation and flowering time genes in early-flowering flax (Linum usitatissimum L.) lines induced by 5-azacytidine
(University of Waterloo, 2007-09-25)Pure-breeding, early-flowering lines of flax, derived from treatment of germinating seeds with 5-azacytdine in 1990, flower 7-13 days before controls, have fewer leaves, are shorter, and have hypomethylated total DNA, ... -
Hydrogen Production and Utilization of Agricultural Residues by Thermotoga Species
(University of Waterloo, 2007-09-26)Abstract: Hydrogen can be a renewable energy source to replace conventional fossil fuels. Compared to current hydrogen production processes by consuming fossil fuels, biological hydrogen production has the advantage of ... -
Molecular Characterization of Toxic Cyanobacteria in North American and East African Lakes
(University of Waterloo, 2007-09-27)Toxic cyanobacterial blooms constitute a threat to the safety and ecological quality of aquatic environments worldwide. Cyclic hepatotoxin, especially microcystin, is the most widely occurring of the cyanotoxins. The aim ... -
STUDY OF SHORT CHAIN DEHYDROGENASE / REDUCTASES (SDRs) IN SINORHIZOBIUM MELILOTI
(University of Waterloo, 2007-09-27)Sinorhizobium meliloti maintains a complex lifestyle, including saprotrophy, rhizophere colonization and root hair infection leading to the formation of root nodules in which the plant provides sustenance in return for ... -
Assessment of hydroecological changes at the Slave River Delta, NWT, using diatoms in seasonal, inter-annual and paleolimnological experiments
(University of Waterloo, 2007-09-27)Relationships between hydrology, limnology and ecology are analyzed in a comprehensive study of water bodies in the Slave River Delta, Northwest Territories, Canada, at a variety of temporal and spatial scales, including ... -
Phytoplankton community composition effects on phosphorus sedimentation dynamics in Lake Erie
(University of Waterloo, 2007-10-01)Cultural eutrophication is caused by the excess addition of phosphorus to aquatic ecosystems, and has long been a water quality management issue in Lake Erie. Despite successful reductions in external loading of phosphorus ... -
Effects of Polycyclic Aromatic Hydrocarbons, Metals and Polycyclic Aromatic Hydrocarbon/Metal Mixtures on Rat Corpus Luteal Cells and Placental Cell Line, JEG-3
(University of Waterloo, 2007-10-01)Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants that can be modified to oxygenated PAH (oxyPAHs) derivatives. It is well known that oxyPAHs tend to be much more reactive than their parent ... -
Plankton Metabolic Balance and its Controlling Factors in the Coastal Zone of the Laurentian Great Lakes
(University of Waterloo, 2007-10-01)Plankton metabolic balance (PMBm) of the surface mixed layer was calculated as the ratio of areal rates of gross photosynthesis (AGP) to community respiration (AR), and estimated for four Laurentian Great Lakes coastal ... -
IN VIVO EPIGENETIC STUDY OF HISTONE ACETYLATION ASSOCIATED WITH OBESITY
(University of Waterloo, 2007-10-02)Post translational modifications in histone proteins are transmissible changes that are not coded for in the DNA sequence itself but have a significant affect in the control of gene expression. Eukaryotic transcription is ... -
An Assessment of Pyridoxine as a Biological Response Modifier During Colon Carcinogenesis
(University of Waterloo, 2007-10-05)The main objective of this proposal was to investigate the effect of vitamin B6 on colon carcinogenesis in vivo. Two in vivo studies were conducted to determine the role of vitamin B6 as a biological modifier of colon ... -
Neural Tube Defect-causing Teratogens Affect Tissue Mechanical Properties and Cytoskeletal Morphology in Axolotl Embryos
(University of Waterloo, 2007-11-22)The teratogenic drugs cytochalasin B and valproic acid have been shown to alter F-actin polymerization, an effect that is crucial in forming microfilaments. Microfilaments form important cytoskeletal structures that maintain ... -
Characterization of iron- and zinc-containing alcohol dehydrogenases from anaerobic hyperthermophiles
(University of Waterloo, 2007-12-18)Hyperthermophiles are microorganisms that can grow at temperatures close to the boiling point of water or above. They are potential resources of thermostable enzymes including alcohol dehydrogenases (ADHs). Both Thermococcus ... -
Organic Tissue Stoichiometry of Cladophora glomerata and its Relation to Coastal Land Use in the Laurentian Great Lakes
(University of Waterloo, 2008-01-04)The relationships between C:N:P (carbon, nitrogen, and phosphorus) stoichiometry of Cladophora glomerata and land use characteristics in selected nearshore areas of the lower Laurentian Great Lakes were determined during ... -
Characterization of the nodulation phenotype of E151, a pleiotropic pea (Pisum sativum L.) mutant.
(University of Waterloo, 2008-01-16)E151 (sym15) is characterized as a pleiotropic pea (Pisum sativum L.) mutant. It has been described as having short lateral roots, a short primary root, and a shorter epicotyl than that of the wild type Sparkle. Furthermore, ... -
Examination of the expression of the heat shock protein gene, hsp110, in Xenopus laevis cultured cells and embryos
(University of Waterloo, 2008-01-16)Prokaryotic and eukaryotic organisms respond to various stressors with the production of heat shock proteins (HSPs). HSP110 is a large molecular mass HSP that is constitutively expressed in most adult mammalian tissues. ... -
Evaluation of indicators of stress in populations of polar bears (Ursus maritimus) and grizzly bears (Ursus arctos)
(University of Waterloo, 2008-01-16)Grizzly and polar bears are both species at the top of the food chain in their respective ecosystems, and as such are indicative of the overall health of the ecosystem. Presently there is little data regarding the stress ...