Browsing Biology by Subject "KNK437"
Now showing items 1-3 of 3
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Effect of heat shock factor inhibitor, KNK437, on stress-induced hsp30 gene expression in Xenopus laevis A6 cells
(University of Waterloo, 2008-05-01)Prokaryotic and eukaryotic organisms respond to various stresses with the production of heat shock proteins (HSPs). HSPs are molecular chaperones that bind to unfolded proteins and inhibit their aggregation as well as ... -
Examination of the effect of the natural plant extract, withaferin A, on heat shock protein gene expression in Xenopus laevis A6 cells
(University of Waterloo, 2010-09-03)In eukaryotes, the ubiquitin-proteasome system (UPS) degrades most cellular protein. Inhibition of the UPS has been associated with different disease states and can affect various intracellular processes including the ... -
Heat Shock Response Inhibition and Gene Expression in <em>Xenopus Laevis</em> Cultured Cells
(University of Waterloo, 2006)Various genes have evolved to protect the cell against stressor-induced damage or death including the heat shock proteins (HSPs). Stressor-induced HSP gene expression involves the activation of heat shock factor (HSF), ...