Browsing Biology by Supervisor "Heikkila, John"
Now showing items 1-3 of 3
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Characterization of Cadmium-Induced BiP Accumulation in Xenopus laevis A6 Kidney Epithelial Cells
(University of Waterloo, 2016-08-19)In vertebrates, cadmium exposure is found to cause respiratory, neurological and kidney disorders. At the cellular level, cadmium can damage or modify proteins resulting in the production of toxic protein aggregates. The ... -
Effect of hemin and baicalein on heme oxygenase-1 accumulation and function in Xenopus laevis cultured cells
(University of Waterloo, 2018-04-26)Heme oxygenase-1 (HO-1) is a stress-inducible enzyme that catalyzes the rate-limiting step in the hemin degradation pathway. Studies in mammalian systems determined that HO-1 promoted cell survival by reducing oxidative ... -
The effect of isothiocyanates on heat shock protein, heme oxygenase-1 and α-tubulin levels and localization in Xenopus A6 kidney cells
(University of Waterloo, 2017-07-19)Numerous studies have elucidated the health promoting properties of organosulfur compounds derived from cruciferous vegetables known as isothiocyanates (ITCs). As electrophiles, the impact of ITCs at the molecular level ...