Browsing Chemistry by Title
Now showing items 180-199 of 842
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Determination of Polycyclic Aromatic Hydrocarbons in Sediment by Pressure-Balanced Cold Fiber Solid Phase Microextraction
(American Chemical Society, 2017-09-20)An improved performance of the cold fiber solid phase micro extraction (CF-SPME) technique was accomplished with the use of the pressure balanced procedure. In order to obtain a pressure-balanced state during extraction ... -
Determining Analytical Potential Energy Functions of Diatomic Molecules by Direct Fitting
(University of Waterloo, 2001)The fully quantum mechanical 'direct-potential-fit' (DPF) method has become increasingly widely used in the reduction of diatomic spectra. The central problem of this method is the representation of the potential energy ... -
Determining Molecular Physicochemical Properties Using Differential Mobility Spectrometry
(University of Waterloo, 2019-09-26)This thesis aims to explore the usage of differential mobility spectrometry (DMS) and quantum chemical calculations to separate and identify drug compounds, as well as the use of machine learning (ML) to predict physicochemical ... -
Determining the native and nonnative effects of myristoylation on the folding and switching of hisactophilin
(University of Waterloo, 2012-09-26)Myristoylation, the covalent linkage of a C14 saturated fatty acyl chain to the N-terminal glycine in a protein, plays an important role in reversible membrane and protein binding in cellular signaling by the modified ... -
Determining the Structures and Properties of Biologically-relevant Ions
(University of Waterloo, 2018-08-09)Gas phase studies of biologically relevant ions are increasing in popularity due to the possibility of high throughput analysis requiring minimum sample concentrations. This thesis explores the potential of differential ... -
Developing a Method to Study Ground State Properties of Hydrogen Clusters
(University of Waterloo, 2014-05-05)This thesis presents the benchmarking and development of a method to study ground state properties of hydrogen clusters using molecular dynamics. Benchmark studies are performed on our Path Integral Molecular Dynamics code ... -
Developing Novel Synthetic Methodologies Using Hypervalent Iodine(III) Reagents and Diazonium- or Iodonium Ylides
(University of Waterloo, 2018-02-14)Hypervalent iodine compounds have been established as useful reagents in synthetic chemistry due to their ease of handling and wide range of chemical reactivity under mild reaction conditions. Reported within are studies ... -
Development and Application of a Consumable-Free Modulator for Comprehensive Two-Dimensional Gas Chromatography
(University of Waterloo, 2024-02-16)Comprehensive two-dimensional gas chromatography (GC×GC), is a separation method recognized as offering far greater peak capacity than conventional one-dimensional separations. Today, the most frequently used GC×GC systems ... -
Development and application of needle trap devices
(University of Waterloo, 2015-10-30)Recently, there has been increasing interest in environmental analysis among the scientific community. Monitoring of organic and inorganic environmental pollutants and investigations into their potential to adversely affect ... -
Development and Application of Solid-Phase Microextraction Probe Electrospray Ionization
(University of Waterloo, 2020-12-21)Ambient ionization mass spectrometry (AIMS) is a category of mass spectrometry (MS) techniques originally characterized as using ambient ionization sources to analyze samples with little to no sample preparation and no ... -
Development and application of SPME technologies for the rapid sampling and analysis of anthropogenic compounds in the environment
(University of Waterloo, 2017-04-27)Due to the wide spread use of pharmaceuticals in both human and animal populations, the contamination of surface waters resulting from the outflow of waste water treatment facilities is of growing concern. Conventional ... -
Development and Application of the Needle Trap Device
(University of Waterloo, 2008-05-08)Air is one of the most important resources in the world and is essential for life. With the development of industry, air pollution is becoming a severe problem. Air Pollution not only affects the quality of the air we ... -
Development and biomedical applications of solid phase micro-extraction (bio-SPME) chemical biopsy devices
(University of Waterloo, 2024-02-22)Micro-sampling is a vital component in modern diagnostics and personalized medicine. In vivo SPME is a novel branch of biomedical applications of SPME (Bio-SPME) that offers unique advantages complementary to existing ... -
Development and characterization of a laminar aerosol flow tube
(AIP, 2006-03)We have developed a new laminar aerosol flow tube (AFT) to study transformations such as ice nucleation, deliquescence, and efflorescence in model atmospheric aerosols. The apparatus consists of four sections which can be ... -
Development and optimization of coated blade spray - mass spectrometry for bioanalytical and clinical applications
(University of Waterloo, 2018-08-23)Bioanalysis is a sub-discipline of analytical chemistry that focuses on the identification and quantification of small and large molecules (e.g. metabolites and proteins) present in biological sample matrices (e.g. blood, ... -
Development and Study of the Microfluidic Open Interface Coupled with Solid-phase Microextraction for Rapid Analysis
(University of Waterloo, 2022-09-28)Analytical chemistry mainly aims to identify and quantify analytes in matrices of interest. Analytical chemistry is an indispensable part of chemistry (and other scientific fields) because identification and quantification ... -
Development and validation of a fully automated solid phase microextraction high throughput method for quantitative analysis of multiresidue veterinary drugs in chicken tissue
(Elsevier, 2019-05-16)This paper presents the development and validation of a fully automated, high-throughput multiclass, multiresidue method for quantitative analysis of 77 veterinary drugs in chicken muscle via direct immersion solid phase ... -
Development and validation of eco-friendly strategies based on thin film microextraction for water analysis
(Elsevier, 2018-12-07)The aim of the current study is the establishment of Green Analytical Chemistry strategies for water analysis by elimination/reduction of hazardous chemicals, energy consumption, and waste generation throughout the entire ... -
Development of 3D Printable, Hydrophilic, and Rapidly Curing Silicone-based Ink Formulations for Various Biomedical Applications
(University of Waterloo, 2023-01-18)3D printing is the use of additive manufacturing techniques to deposit materials layer-by-layer. Compared to alternative tissue fabrication methods such as casting, 3D printing is unique, because it uses CT and MRI scans ... -
Development of a Carbon Mesh Supported Thin Film Microextraction Membrane As a Means to Lower the Detection Limits of Benchtop and Portable GC/MS Instrumentation
(American Chemical Society, 2015-12-18)In this work, a durable and easy to handle thin film microextraction (TFME) device is reported. The membrane is comprised of poly(divinylbenzene) (DVB) resin particles suspended in a high-density polydimethylsiloxane (PDMS) ...