Browsing Chemistry by Title
Now showing items 627-646 of 842
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The Reproductive Effects of Municipal Wastewater Effluents
(University of Guelph, 2017-03-01)There is a growing concern that pharmaceuticals and other chemicals present in the effluents (sewage discharged into a river) from municipal wastewater treatment plants enter the aquatic environment, where they may affect ... -
Reversible and Mechanism-Based Irreversible Inhibitor Studies on Human Steroid Sulfatase and Protein Tyrosine Phosphatase 1B
(University of Waterloo, 2009-10-02)The development of reversible and irreversible inhibitors of steroid sulfatase (STS) and protein tyrosine phosphatase 1B (PTP1B) is reported herein. STS belongs to to the aryl sulfatase family of enzymes that have roles ... -
Reversible gating of ion transport through DNA-functionalized carbon nanotube membranes
(Royal Society of Chemistry, 2017-01-03)Carbon nanotubes (CNTs) can be used to create unique fluidic systems for studying ion transport in nanochannels due to their well-defined geometry, atomically smooth and chemically inert surface, and similarity to transmembrane ... -
Review of geometries and coating materials in solid phase microextraction: Opportunities, limitations, and future perspectives
(Elsevier, 2017-09-01)The development of new support and geometries of solid phase microextraction (SPME), including metal fiber assemblies, coated-tip, and thin film microextraction (TFME) (i.e. self-supported, fabric and blade supported), as ... -
The Role of Carbonic Anhydrase in Promoting CO2 Capture and Operation of Bicarbonate-Fed Electrolyzers
(University of Waterloo, 2022-08-23)Capturing CO2 through chemical absorption offers a sustainable solution to mitigate rising CO2 emissions which are widely agreed to be the primary contributor to climate change. Among various capture solutions, bicarbonate ... -
Role of NOS-like proteins found in bacteria
(University of Waterloo, 2007-01-22)Nitric oxide (•NO) is a molecule with diverse biological effects involved in both signaling and defense mechanisms in mammalian systems. The production of •NO is catalyzed from L-Arginine by a family of enzymes known as ... -
Role of Symmetry in Hisactophilin Folding
(University of Waterloo, 2009-02-23)Hisactophilin is a histidine-rich actin binding protein from Dictyostelium discoideum; it is a member of the β-trefoil superfamily and exhibits a characteristic tertiary structure with three-fold symmetry. The effect of ... -
The Role of Wastewater Testing for SARS-CoV-2 Surveillance
(Ontario COVID-19 Science Advisory Table, 2021-08-26)Wastewater testing for SARS-CoV-2 is relatively new; however, it builds on existing public health surveillance infrastructure. There is a limited but growing evidence base for its use, despite notable interpretation ... -
The Saliva Exposome for Monitoring of Individuals’ Health Trajectories
(Environmental Health Perspectives - United States Federal Government, 2017-07-20)Background: There is increasing evidence that environmental, rather than genetic, factors are the major causes of most chronic diseases. By measuring entire classes of chemicals in archived biospecimens, exposome-wide ... -
Scanning Tunneling Microscopy of Electrically Driven Phase Transitions in a Charge Density Wave Material
(University of Waterloo, 2022-03-25)The 1T polytype of the van der Waals material TaS2, has been studied extensively as a strongly correlated system. Exhibiting several different charge density wave (CDW) states, the phase diagram of 1T-TaS2 has been explored ... -
Searching for a DNAzyme version of the leadzyme
(Springer, 2015-10-12)The leadzyme refers to a small ribozyme that cleaves a RNA substrate in the presence of Pb2+. In an optimized form, the enzyme strand contains only two unpaired nucleotides. Most RNA-cleaving DNAzymes are much longer. Two ... -
Selection and characterization of an aptamer to a thiazole orange derivative for use in a fluorescence-based biosensor
(University of Waterloo, 2023-08-18)Aptamers are short single-stranded DNA or RNA sequences that have been selected in vitro to have a high binding affinity to a specific target molecule. One class of aptamers can bind to small non-fluorescent molecules to ... -
A Selective Na+ Aptamer Dissected by Sensitized Tb3+ Luminescence
(Wiley, 2016-08-17)A previous study of two RNA-cleaving DNAzymes, NaA43 and Ce13d, revealed the possibility of a common Na+ aptamer motif. Because Na+ binding to DNA is a fundamental biochemical problem, the interaction between Ce13d and Na+ ... -
Selective Surface Chemistry of Bifunctional Carboxylic acid, Aldehyde and Alcohol on Si(100)2x1: Exploring Competition between Alkyl, Alkenyl, Carboxyl, Hydroxyl, and Carbonyl Groups in Surface Functionalization
(University of Waterloo, 2009-01-26)The dissociative adsorption of three carboxylic acids (acetic acid, propanoic acid, and acrylic acid), allyl alcohol, and allyl aldehyde on Si(100)2×1 at room temperature has been investigated by X-ray photoelectron ... -
Self-assembled gold nanochain based materials as building blocks to fabricate flexible devices and electrocatalysts
(University of Waterloo, 2021-08-25)1D metal nanostructures are being actively researched as a component in next-generation electronic devices and as highly efficient electrocatalysts. 1D gold nanomaterials can be designed by controlling the aspect ratio and ... -
Self-association of Oligoquinoline Foldamers Probed by Time-Resolved Fluorescence Anisotropy
(University of Waterloo, 2022-01-31)The self-associations of oligoquinoline-based foldamers (OPV-QₙA with n = 4, 8, 17, and 33) terminated at one end with a carboxylic acid (A) and at the other end with the fluorescent dye oligo(phenylene vinylene) (OPV) ... -
Self-healable and reversible liposome leakage by citrate-capped gold nanoparticles probing initial adsorption/desorption induced lipid phase transition
(Royal Society of Chemistry, 2015-10-14)We herein report that the adsorption/desorption of citrate-capped gold nanoparticles (AuNPs) transiently causes leakage in fluid phase DOPC liposomes, while the liposomes do not leak with AuNPs capped with mercaptopropionic ... -
Self-healing metal coordinated hydrogels using nucleotide ligands
(Royal Society of Chemistry, 2015-10-21)A supramolecular gel formed by coordination of Zn2+ with adenosine monophosphate (AMP) is reported. The adenine base, the monophosphate, and Zn2+ are all important for gel formation. Mechanically disrupted gels can re-form ... -
Semiquinone-Bridged bis-Dithiazolyls as Neutral Radical Conductors
(University of Waterloo, 2011-12-21)Radicals are potential building blocks to prepare conductive and magnetic materials. In order to achieve high conductivity, materials displaying a large bandwidth W and a low on-site Coulomb repulsion energy U must be ... -
Sensing Parts-per-Trillion Cd2+, Hg2+ and Pb2+ Collectively and Individually Using Phosphorothioate DNAzymes
(American Chemical Society, 2014-05-22)Cadmium, mercury, and lead are collectively banned by many countries and regions in electronic devices due to their extremely high toxicity. To date, no sensing method can detect them as a group and also individually with ...