Browsing Optometry and Vision Science by Title
Now showing items 114-133 of 249
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Impact of contact lens wear on epithelial alterations in keratoconus
(Elsevier, 2021-03)Purpose The purpose of this study was to characterize the central epithelial thickness (CET) of penetrating keratoplasty corneal specimens obtained from patients with keratoconus (KC) and correlate the histological patterns ... -
Impact of in vitro Tear Film Composition on Lysozyme Deposition and Denaturation
(University of Waterloo, 2012-08-31)Purpose To study the impact of lactoferrin and lipids on the kinetic deposition and denaturation of lysozyme on contact lens materials. Methods The contact lenses investigated in this thesis included two silicone ... -
Impact of Light Scatter on the Assessment of Retinal Arteriolar Hemodynamics
(University of Waterloo, 2010-04-29)Introduction and Purpose: Vascular pathologies play an important role in the etiology and progression of number of ocular diseases. Many instruments are developed to monitor retinal hemodynamics, including the Canon Laser ... -
Impact of Wavefront-Guided Laser in situ Keratomileusis on Monochromatic Higher Order Aberrations and Vision
(University of Waterloo, 2008-07-04)Wavefront-guided (WFG) laser in situ keratomileusis (LASIK) differs from conventional surgery by applying a refined algorithm for tissue removal, based on information from preoperative wavefront aberration data. Since the ... -
Impression Cytology of the Lid Wiper Area
(Journal of Visualized Experiments, 2016-09-08)Few reports on the cellular anatomy of the lid wiper (LW) area of the inner eyelid exist and only one report makes use of cytological methods. The optimization of a method of collecting, staining and imaging cells from the ... -
In vitro analysis of wettability and physical properties of blister pack solutions of hydrogel contact lenses
(University of Waterloo, 2010-04-30)Contact lens success is primarily driven by comfort of the lens in eye. Over the years, many modifications have been made to the lens surface and bulk material to improve comfort of the lens, however 50% of contact lens ... -
In vitro and ex vivo wettability of hydrogel contact lenses
(University of Waterloo, 2006)The wettability of contact lenses has become an area of intense research, with the belief that the more "hydrophilic" or wettable the lens surface is, the more comfortable the lens may be, as the posterior surface of the ... -
In Vitro and In Vivo Evaluation of Novel Ciprofloxacin-Releasing Silicone Hydrogel Contact Lenses
(Association for Research in Vision and Ophthalmology, 2014-08-08)Purpose.: The purpose of this study was to evaluate ciprofloxacin-releasing silicone hydrogel contact lens materials in vitro and in vivo for the treatment of microbial keratitis. Methods.: Model silicone hydrogel contact ... -
In Vitro Competitive Binding of Major Tear Proteins to Contact Lenses
(University of Waterloo, 2013-09-27)Purpose To study the impact of incubation solution complexity on protein deposition to silicone hydrogel (SH) contact lenses and the effect of contact lens cleaning solutions on protein activity and removal. Methods The ... -
In Vitro Release of Inflammatory Cytokines from Contact Lens Materials
(University of Waterloo, 2020-12-22)The upregulation of inflammatory mediators in the tear film during contact lens wear indicates that lens wear may induce an inflammatory response on the ocular surface. Previous research has investigated the relationship ... -
In vitro ultraviolet–induced damage in human corneal, lens, and retinal pigment epithelial cells
(Molecular Vision, 2011-01-21)Purpose: The purpose was to develop suitable in vitro methods to detect ocular epithelial cell damage when exposed to UV radiation, in an effort to evaluate UV-absorbing ophthalmic biomaterials.Methods: Human corneal ... -
In Vivo Imaging of Corneal Conditions using Optical Coherence Tomography
(University of Waterloo, 2006)Purposes: To use optical coherence tomography (OCT) to image and quantify the effect of various corneal conditions, in terms of corneal, stromal and epithelial thickness, and light backscatter. To assess the changes ... -
Influence of Conjunctival Folds on Calculated Tear Meniscus Volume Along the Lower Eyelid
(Elsevier, 2016-05-03)Purpose: In calculating tear meniscus volume (TMV), tear meniscus height (TMH), radius (TMR) and cross-sectional area (TMA) are usually measured at the center of the lower lid margin, but lid-parallel conjunctival folds ... -
Infrared Imaging of Meibomian Glands and Evaluation of the Lipid Layer in Sjogren's Syndrome Patients and Nondry Eye Controls
(Association for Research in Vision and Ophthalmology, 2015-05-02)Purpose.: The purpose of this study was to evaluate meibomian gland dropout and lipid layer thickness (LLT) in patients with and without Sjögren's syndrome dry eye (SS). Methods.: We recruited 11 participants with SS ... -
Inhibition of Defocus-Induced Myopia in Chickens
(Association for Research in Vision and Ophthalmology, 2013-04-12)Purpose.: To determine the effect of wearing a lens with a unique peripheral optical design on the development and progression of defocus-induced myopia in newly hatched chickens.Methods.: Eighty-five newly hatched chickens ... -
Insights to Using Contact Lenses for Drug Delivery
(Omics International, 2013)There has been considerable interest in the potential application of contact lenses for ocular drug delivery. This short communication provides an overview of the challenges faced by delivering drugs using contact lenses, ... -
Interaction of Tear Inflammatory Markers with Contact Lens Materials
(University of Waterloo, 2020-01-28)Biomaterials are natural or synthetic materials that come into contact with biological tissue. Contact lenses are the most commonly used biomaterials, being worn by an estimated 140 million people worldwide. While contact ... -
Investigating the Effect of Mild TBI on the Global Processing of Form and Motion
(University of Waterloo, 2018-09-10)Purpose: Individuals with mild traumatic brain injury (TBI) often experience a range of visual symptoms. The cortical processing of visual information involves two parallel streams; the ventral stream (form perception) and ... -
Investigating the enhancement of visual cortex plasticity through non-invasive brain stimulation
(University of Waterloo, 2024-01-02)Purpose: (1) To investigate the effects of various non-invasive brain stimulation (NIBS) modalities, including high-frequency transcranial random noise stimulation (hf-tRNS), anodal transcranial direct current stimulation ... -
Investigating The Impact of Multipurpose Solutions Released From Silicone Hydrogel Lenses on Corneal Epithelial Cells, in vitro
(University of Waterloo, 2010-01-22)Cytotoxicity of Multi-Purpose Solutions (MPS) is commonly tested on cells using diluted MPS or extracts from MPS soaked contact lenses. There is evidence that lens type will affect uptake and release of compounds contained ...