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    • Structural and Kinetic Studies on the Potent Inhibition of Metallo-β-Lactamases by 6- Phosphonomethylpyridine-2-Carboxylates 

      HInchliffe, Philip; Tanner, Carol A.; Krismanich, Anthony; Labbé, Geneviève; Goodfellow, Valerie J.; Marrone, Laura; Desoky, Ahmed; Calvopiña, Karina; Whittle, Emily E.; Zeng, Fanxing; Avison, Mathew B.; Bols, Niels C.; Siemann, Stefan; Spencer, James; Dmitrienko, Gary I. (American Chemical Society, 2018-02-27)
      There are currently no clinically available inhibitors of metallo-β-lactamases (MBLs), enzymes which hydrolyze β-lactam antibiotics and confer resistance on Gram-negative bacteria. Here we present 6-phosphonomethylpyridi ...


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