Browsing Pharmacy by Supervisor "Foldvari, Marianna"
Now showing items 1-3 of 3
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Development of in vitro 3D model systems for screening non-viral neurotrophic factor gene therapies for the retina
(University of Waterloo, 2018-08-21)Glaucoma is a neurodegenerative disease that can lead to a complete loss of vision due to retinal ganglion cell (RGC) death. Therapies that have the capacity to protect and rescue stressed RGCs remain a critical unmet need ... -
Development of Peptide-Modified Gemini Nanoplexes for Gene Delivery to the Retina
(University of Waterloo, 2020-04-22)Glaucoma is a retinal neurodegenerative disease where the retinal ganglion cells (RGCs) suffer from damage and die over time due to multiple factors, including a persistently elevated intraocular pressure (IOP). Glaucoma ... -
Improving the delivery and immunogenicity of an inhalable CpG-ODN DNA vaccine by bio-adhesive gemini nanoparticles in neonatal chickens
(University of Waterloo, 2018-01-05)Cytosine-phosphodiester-guanine oligodeoxynucleotides (CpG-ODN) are nucleotide sequence motifs found in the bacterial genome that activate the mammalian innate immune response and have been found to boost humoral immunity ...