Browsing Biology by Title
Now showing items 368-387 of 597
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Magnetic Force Microscopy (MFM) Characterization of Superparamagnetic Nanoparticles (SPIONs)
(University of Waterloo, 2012-09-28)Superparamagnetic iron oxide nanoparticles (SPIONs), due to their controllable sizes, relatively long in vivo half-life and limited agglomeration are ideal for biomedical applications such as magnetic labeling, hyperthermia ... -
The mammalian skin microbiome
(University of Waterloo, 2017-08-23)Skin constitutes the primary physical barrier between mammals and their external environment. Characterization of the microorganisms on skin is essential for understanding how a host evolves in association with its microbial ... -
The Marine Feeding Habits of Atlantic Salmon (Salmo salar L.) in the Northwest Atlantic
(University of Waterloo, 2016-06-07)Investigations on marine feeding of Atlantic salmon (Salmo salar L.) in the Northwest Atlantic are rather limited in comparison with studies carried out in the Northeast Atlantic. Climate induced changes to food webs in ... -
Measurement of Surface Tensions in Aggregated Cells of the Embryonic Chick
(University of Waterloo, 2008-01-23)Cell surface properties are crucial to the mechanisms by which groups of cells organize themselves during embryogenesis, cancer metastases and tissue engineering. Measured surface tension values provide a quantitative ... -
Measurement of Tensile Forces in Xenopus laevis Neural Tissue
(University of Waterloo, 2010-01-22)Neurulation is critical for the proper development of the central nervous system during embryogenesis. This process requires coordinated morphogenetic movements driven by localized cell movements. The key morphogenetic ... -
Mechanistic Role of ARNT/HIF-1β in the Regulation of Glucose-Stimulated Insulin Secretion
(University of Waterloo, 2014-04-29)Loss of glucose-stimulated insulin secretion (GSIS) from the pancreatic beta-cells is one of the earliest detectable defects in the pathogenesis of type 2 diabetes. However, despite its relevance, the mechanisms that govern ... -
Mercury dynamics in the anadromous Arctic char (Salvelinus alpinus) and food webs of inner Frobisher Bay, Nunavut
(University of Waterloo, 2022-07-06)Mercury (Hg) is a ubiquitous toxic metal that bioaccumulates in organisms and biomagnifies in food webs. Evaluating Hg bioaccumulation and biomagnification in Arctic marine ecosystems is critical for understanding Hg ... -
Metabolic Engineering Sinorhizobium meliloti and Pseudomonas putida for Novel Polymer Production
(University of Waterloo, 2015-03-03)S. meliloti belongs to nitrogen-fixing Rhizobia, the members of the Rhizobiales order of the α-proteobacteria. It can establish a symbiotic relationship with the Leguminosae family of flowering plants. In addition, it is ... -
Metabolic engineering strategies for biomanufacturing of chemicals using Yarrowia lipolytica and Escherichia coli
(University of Waterloo, 2024-04-24)This dissertation advances metabolic engineering by optimizing the genetic and metabolic capabilities of Yarrowia lipolytica and Escherichia coli to enhance their applications in biotechnology. It focuses on improving Y. ... -
A Metagenomic Examination of Virus Diversity, Host Interactions, and Genetic Potential Across Municipal Waste Sites
(University of Waterloo, 2023-09-18)Viruses are the most abundant microbial guild on the planet, impacting microbial community structure and ecosystem services. Despite this, they have been underrepresented in reference databases compared to Bacteria and ... -
Metal Mixture Toxicity to Hyalella azteca: Relationships to Body Concentrations
(University of Waterloo, 2008-01-25)A literature review of metal mixture interaction analyses identified that there was not a consistent method to determine the impact of metal mixtures on an aquatic organism. The review also revealed that a majority of the ... -
Metal Uptake and Toxicity in Rainbow Trout (Oncorhynchus mykiss) When Exposed to Metal Mixtures Plus Natural Organic Matter
(University of Waterloo, 2008-05-22)Multiple metal-gill modelling based on the toxic unit concept suggests that metals with the same toxic actions (e.g. Pb and Cd interacting at Ca-gill channels) will exhibit strictly additive binding at the gills of fish ... -
Method development for the analysis of soil bacterial communities
(University of Waterloo, 2015-01-23)Due to the tremendous diversity and abundance of microbes in environmental and host-associated environments, adequate characterization of these samples remains a challenge for microbiologists. In order to increase the depth ... -
Microbial communities of wastewater in the Canadian Arctic
(University of Waterloo, 2020-01-20)Wastewater management in the Canadian Arctic is challenging due to the extreme climate and lack of conventional treatment system infrastructure. To resolve these issues, most Northern communities use waste stabilization ... -
Microbial Community Compositional Stability in Agricultural Soils During Freeze-Thaw and Fertilizer Stress
(University of Waterloo, 2024-01-22)Microbial activity persists in cold region agricultural soils during the fall, winter, and spring (i.e., non-growing season) and frozen condition, with peak activity during thaw events. Climate change is expected to change ... -
Microbial Composition and Functional Diversity in Waste Environments
(University of Waterloo, 2023-01-09)Landfilling remains the most common endpoint of discarded waste. At landfill sites, waste is transformed and degraded by microbially mediated processes conducted by different trophic groups, comprised of members of a ... -
Microbial diversity and cellulosic capacity in municipal waste sites
(University of Waterloo, 2019-01-25)Cellulose is the most abundant organic compound found on earth. Cellulose’s recalcitrance to hydrolysis is a major limitation to improving the efficiency of industrial applications. The biofuel, pulp and paper, agriculture, ... -
Microbial ecology of ammonia oxidation in the Grand River
(University of Waterloo, 2014-08-28)The Grand River is the largest catchment in Southern Ontario and is heavily impacted by the results of human activities, including wastewater effluent and agricultural and urban runoff. Ammonia oxidation is an important ... -
Microbial Ecology of Phototrophs in Iron-rich Boreal Shield Lakes
(University of Waterloo, 2020-09-24)The early Earth oceans of the Archaean Eon (approx. 3.8-2.5 billion years ago) are thought to have been predominantly anoxic with ferruginous waters containing high levels of dissolved ferrous iron and low levels of sulfate. ... -
Microbiology of Barrier Component Analogues of a Deep Geological Repository
(University of Waterloo, 2020-09-18)Many countries are in the process of designing and implementing long-term storage solutions for used nuclear fuel. Like many of these countries, Canada is considering a deep geological repository (DGR) wherein used fuel ...