Browsing Biology by Title
Now showing items 61-80 of 597
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The carbon and nitrogen composition of suspended particulate matter in Lake Erie, selected tributaries, and its outflow
(University of Waterloo, 2005)Since their introduction to Lake Erie, dreissenid mussels may have reengineered the cycling of nutrients in the lake so that the nearshore benthic community intercepts, retains, and recycles greater quantities of nutrients. ... -
Carbon Metabolism and Desiccation Tolerance in the Nitrogen-Fixing Rhizobia Bradyrhizobium japonicum and Sinorhizobium meliloti
(University of Waterloo, 2009-04-22)Most members of the Rhizobiaceae possess single copies of the poly-3-hydroxybutyrate biosynthesis genes, phbA, phbB and phbC. Analysis of the genome sequence of Bradyrhizobium japonicum reveals the presence of five homologues ... -
cDNA?GFP Fusion Libraries for Analyses of Protein Localization in Mouse Stem Cells
(University of Waterloo, 2005)Stem cells have great potential value for treating a number of diseases and conditions, including diabetes, Parkinson's, and spinal cord injuries. Applying stem cells for therapeutic purposes will require an in-depth ... -
Celastrol, a proteasome inhibitor, can induce the expression of heat shock protein genes in Xenopus cultured cells
(University of Waterloo, 2010-01-25)Heat shock proteins (HSPs) are stress-inducible and evolutionarily conserved molecular chaperones that are involved in protein binding and translocation. As molecular chaperones, HSPs bind to denatured proteins, inhibit ... -
Cell Cultures from Walleye (Sander vitreus) for Use in Cell Biology and Virology
(University of Waterloo, 2014-09-16)This thesis has developed from the walleye, Sander vitreus (Mitchill), cell lines (WE) and used them to study viral hemorrhagic septicemia virus (VHSV IVb), which is the causative agent for viral hemorrhagic septicaemia ... -
Changes in Gill Physiology and Energy Requirements of Darter Species (Etheostoma spp.) due to Effluent in the Grand River
(University of Waterloo, 2020-08-18)The effluent from municipal wastewater treatment plants is a major point source of contamination in Canadian waterways. Improvement of effluent quality to reduce contaminants like pharmaceuticals and personal care products, ... -
Changes in the biological characteristics of Canadian Arctic charr (Salvelinus alpinus) populations in response to climate-induced environmental variation
(University of Waterloo, 2008-05-01)Abstract The thesis includes two studies of Arctic charr, Salvelinus alpinus, responses to climate variation. In the first chapter, site-specific data from a fishery on the Hornaday River, Northwest Territories (NWT), are ... -
Characterization and Analysis of the Microbiota of Bangia atropurpurea and other Freshwater and Marine Algae in North America
(University of Waterloo, 2021-09-14)Algae are a diverse polyphyletic group of photosynthetic organisms that contribute to forming rich ecosystems within marine and freshwater habitats. Many factors contribute to algal function and growth, such as the chemistry ... -
Characterization and expression patterns of five Winter Rye β-1,3-endoglucanases and their role in cold acclimation
(University of Waterloo, 2007-01-23)Winter rye produces ice-modifying antifreeze proteins upon cold treatment. Two of these antifreeze proteins are members of the large, highly conserved, β-1,3-endoglucanase family. This project was designed to identify ... -
Characterization and Genetic Manipulation of D-cysteine Desulfhydrase from Solanum lycopersicum
(University of Waterloo, 2008-05-15)Progress in DNA sequencing of plant genomes has revealed that, in addition to microorganisms, a number of plants contain genes which share similarity to microbial 1-aminocyclopropane-1-carboxylate (ACC) deaminases. ACC ... -
Characterization of Active Cellulolytic Consortia from Arctic Tundra
(University of Waterloo, 2011-05-20)The consortia of microorganisms responsible for the hydrolysis of cellulose in situ are at present poorly characterized. Nonetheless, the importance of these communities is underscored by their capacity for converting ... -
CHARACTERIZATION OF AHR SIGNALING AND THE IMPACT OF POLYCHLORINATED BIPHENYLS ON THE ADAPTIVE RESPONSES TO STRESS IN FISH
(University of Waterloo, 2007-09-13)Persistent organic pollutants (POPs), including polychlorinated biphenyls (PCBs) are widespread in aquatic systems. These toxicants bioaccumulate in the tissues of aquatic organisms, especially fish as they occupy a position ... -
Characterization of Alcohol Dehydrogenases from Hyperthermus butylicus
(University of Waterloo, 2016-01-22)Hyperthermophiles grow optimally at 80 oC and above, and many of them use carbohydrates and peptides for their growth. Hyperthermus butylicus is a peptide-fermenting hyperthermophilic archaeon producing 1-butanol as an ... -
Characterization of Cadmium-Induced BiP Accumulation in Xenopus laevis A6 Kidney Epithelial Cells
(University of Waterloo, 2016-08-19)In vertebrates, cadmium exposure is found to cause respiratory, neurological and kidney disorders. At the cellular level, cadmium can damage or modify proteins resulting in the production of toxic protein aggregates. The ... -
The characterization of checkpoint kinase 2 in Oncorhynchus mykiss: Tissue specific expression suggests biomarker potential
(University of Waterloo, 2007-09-05)Chk2 is a cell cycle checkpoint kinase that is essential for initiating the DNA damage response in the presence of genetic damage. Its role is highly conserved from budding yeast (where it is named Rad53) to humans. Very ... -
The characterization of Dbf4 interactions and roles in genome replication and stability in Saccharomyces cerevisiae
(University of Waterloo, 2020-03-05)Dbf4-dependent kinase (DDK) is a complex composed of the Cdc7 kinase and its regulatory subunit, Dbf4. Initiation of eukaryotic DNA replication requires phosphorylation of Mcm2-7 helicase by DDK. Due to its essential role ... -
Characterization of Dbf4 structure and function in Saccharomyces cerevisiae DNA replication and checkpoint responses.
(University of Waterloo, 2014-02-21)The Dbf4/Cdc7 kinase complex is required for the initiation of DNA replication and promotes this by acting upon members of the Mcm2-7 helicase. In addition to its role in replication, Dbf4/Cdc7 is a target of the S-phase ... -
Characterization of Dissolved Organic Matter and Reduced Sulfur in Coastal Marine and Estuarine Environments: Implications for Protective Effects on Acute Copper Toxicity
(University of Waterloo, 2009-05-13)Copper-induced toxicity in aqueous systems depends on its speciation and bioavailability. Dissolved organic matter (DOM) and reduced sulfur species can complex copper, influencing speciation and decreasing bioavailability. ... -
Characterization of Eukaryotic Translation Initiation Factor 5A isoforms (eIF-5A1 & eIF-5A2) using human cell lines as a model system
(University of Waterloo, 2006)Eukaryotic translation initiation factor 5A (eIF-5A) is the only known cellular protein that contains the post-translationally derived amino acid, hypusine. Initially, eIF-5A was named as a translation initiation factor ... -
Characterization of Eukaryotic Translation Initiation Factor 5A-2 (eIF5A-2) in <i>Arabidopsis thaliana</i>: Effects of Wounding and Pathogen Attack
(University of Waterloo, 2004)Plants respond to wounding and pathogen ingress by synthesizing defence proteins that facilitate wound healing, cell death or provide protection against further pathogen attack. The accumulation of these proteins is ...