Browsing Biology by Title
Now showing items 120-139 of 599
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Cloning and expression of Cyt2Aa1 toxin and characterization of its mode of action
(University of Waterloo, 2010-05-19)The discovery of the pore-forming toxins produced by Bacillus thuringiensis, which are toxic to insects but not to mammalians, has provided a new successful means to control harmful plant-feeding insects biologically. The ... -
Coinfection takes its toll: Sea lice override the protective effects of vaccination against a bacterial pathogen in Atlantic salmon
(Springer Nature, 2017-12-19)Vaccination is considered crucial for disease prevention and fish health in the global salmon farming industry. Nevertheless, some aspects, such as the efficacy of vaccines, can be largely circumvented during natural ... -
Community Surveillance of Omicron in Ontario: Wastewater-based Epidemiology Comes of Age
(Research Square, 2022-03-15)Wastewater-based surveillance of SARS-CoV-2 RNA has been implemented at building, neighbourhood, and city levels throughout the world. Implementation strategies and analysis methods differ, but they all aim to provide rapid ... -
Community-partnered research on subsistence char fisheries near Kugluktuk, Nunavut: novel insights from traditional knowledge and western science
(University of Waterloo, 2023-09-26)Arctic char (Salvelinus alpinus) and Dolly Varden (S. malma) are the two most closely related species in the genus Salvelinus. Both species show substantial intraspecific variation in ecology, life history, morphology, and ... -
Comparative analysis and visualization of microbial gene neighborhoods: applications to pathogen genomics
(University of Waterloo, 2023-12-20)Gene neighborhoods are clusters of genes that are encoded together within the same genomic region, and may share similarity in expression and/or function. Bioinformatic analysis of gene neighborhoods is a powerful approach ... -
A Comparative Analysis of 4 Shallow Urban Impoundments
(University of Waterloo, 2010-08-11)Shallow urban impoundments are known for low water transparency, and generally low water quality. This thesis investigates the effects of land use, management regime, and carp density on the water quality in 4 shallow urban ... -
Comparative functional analysis of two alpha-glucosidases, Family 31 Glycoside Hydrolases from the human gut symbiont Bacteroides thetaiotaomicron
(University of Waterloo, 2012-04-18)The human gut is home to a significant number of microorganisms including the dominant symbiont Bacteroides thetaiotaomicron. This microbe is predicted to possess an array of glycoside hydrolases, majority of which are ... -
Comparative metagenomics of PHA synthase genes in soil
(University of Waterloo, 2017-01-19)Polyhydroxyalkanoates (PHAs) are biopolymers produced naturally by bacteria. They are of considerable scientific interest as fundamental components of bacterial carbon metabolism and have biotechnological applications as ... -
Comparative Phylogeography of North American Diporeia hoyi and Gammarus lacustris (order: Amphipoda)
(University of Waterloo, 2010-01-06)This thesis examines the phylogeographic distribution of both Diporeia hoyi and North American populations of Gammarus lacustris. The first section of this thesis investigates the genetic distribution and species composition ... -
A comparative study of gemini surfactants 16-3-16 and 16-7NH-16 as possible microbubble gene carriers
(University of Waterloo, 2011-01-17)Gene therapy holds great promise to treat a variety of human diseases, including diabetes. The development of a new gene delivery system called Ultrasound Targeted Microbubble Destruction (UTMD) has been developed to enhance ... -
The Compared Effects of Lithium Isotopes ⁶Li and ⁷Li on GSK-3-β Activity and the Biochemistry of HT22 Neuronal Cells
(University of Waterloo, 2020-12-09)The use of lithium in treatment of mental illnesses like bipolar disorder, major depressive disorder, and schizophrenia dates to the mid 20th century. Some research also indicates that the symptoms of Alzheimer’s Disease ... -
Comparing habitat use and mercury accumulation in Arctic Grayling (Thymallus arcticus) from two northern ecosystems
(University of Waterloo, 2018-08-27)An improved understanding of the distribution and habitat requirements for mountain stream populations of Arctic Grayling (Thymallus arcticus) is necessary to assess their vulnerability to environmental stressors, establish ... -
Complete genome sequence of the fish pathogen Flavobacterium psychrophilum ATCC 49418T
(BioMed Central, 2015-01-21)Flavobacterium psychrophilum is the causative agent of bacterial cold water disease and rainbow trout fry mortality syndrome in salmonid fishes and is associated with significant losses in the aquaculture industry. The ... -
Consequences of cytochrome c oxidase assembly defects for the yeast stationary phase
(Elsevier, 2018-06-01)The assembly of cytochrome c oxidase (COX) is essential for a functional mitochondrial respiratory chain, although the consequences of a loss of assembled COX at yeast stationary phase, an excellent model for terminally ... -
Considerations of Varied Thermoregulatory Expressions in Migration Theory
(Wiley, 2021-10)Optimal migration theory has been used for 3 decades to generate predictions of stopover behavior and understand migration ecology. Yet, to date, there have been no attempts to understand the impacts of thermoregulation ... -
CONSTRUCTION AND OPTIMIZATION OF A ssDNA VECTOR PRODUCTION SYSTEM FOR GENE THERAPY PLATFORM
(University of Waterloo, 2023-06-15)Viral capsid of Anellovirus and ssDNA reporter constructs carrying an anellovirus intergenic region were both produced separately in E. coli systems, purified and then mixed together in an in vitro system. At particular ... -
Contaminants and Nutrients in Traditional Food Fishes in Kluane Lake, YT
(2016-06)The outcomes of a collaborative project led by the Kluane First Nation (KFN), in partnership with the Arctic Institute of Community-Based Research (AICBR), the University of Waterloo, and Western University, are presented ... -
Contrasting physiological responses between invasive sea lamprey and non-target bluegill in response to acute lampricide exposure
(Elsevier, 2021-08-01)Control of invasive sea lamprey (Petromyzon marinus) in the Laurentian Great Lakes of North America uses lampricides, which consist of 3-trifluoromethyl-4-nitrophenol (TFM) and niclosamide. Lampricides are thought to inhibit ... -
Controls of Fish Mercury Concentrations in Subarctic Lakes of Canada
(University of Waterloo, 2022-07-25)Mercury (Hg) is a global pollutant that in its organic and more toxic form, methyl Hg (MeHg), can cause detrimental health effects on fish, wildlife, and humans. In lake ecosystems, concentrations of Hg ([Hg]) in fish ... -
Cytochrome c Oxidase Deficiency: Study of Aberrant Phenotypes and their Connection to Secondary Functions of Assembly Factors
(University of Waterloo, 2017-12-14)Mitochondria are double membrane-bound organelles present in all eukaryotic organisms and are involved in myriad cellular pathways. Cytochrome c oxidase (COX) is a mitochondrial inner membrane protein complex that is an ...